| BioID | bio2763 |
|---|
| Name | TALNETANT |
|---|
| ChEMBL ID | CHEMBL10188 |
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| Molecular Formula | C25H22N2O2 |
|---|
| Molecular Weight | 382.46 |
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| Molecular Weight (Monoisotopic) | 382.1681 |
|---|
| Type | Small molecule |
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| Max Phase | Phase 2 |
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| Target ID | Tar12 |
|---|
| Target Name | Toll-like receptor 9 (TLR9) |
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| Synonyms | SB-2234|SB-223412|TALNETANT|Talnetant |
|---|
| Smiles | CC[C@H](NC(=O)c1c(O)c(-c2ccccc2)nc2ccccc12)c1ccccc1 |
|---|
| Inchi | InChI=1S/C25H22N2O2/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18/h3-16,20,28H,2H2,1H3,(H,27,29)/t20-/m0/s1 |
|---|
| Inchi Key | BIAVGWDGIJKWRM-FQEVSTJZSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 36.0 |
|---|
| Bioactivities | 123.0 |
|---|
| Np Likeness Score | -0.68 |
|---|
| Records Key | ['1', '7c', '1, SB-223412, Talnetant', 'SB-223412', '54', '2, SB-223412', '1', '1a', '2a', 'TALNETANT', 'TALNETANT', '1786', '3', 'Talnetant', 'Talnetant', '1a', 'TALNETANT', 'Talnetant', 'TALNETANT', 'TALNETANT', 'AZ100', '4, talnetant, SB 223412', 'Talnetant', 'COVC-1752592883'] |
|---|
| Records Name | ['3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide', '3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide', '(S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide', 'talnetant', '3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide', 'Talnetant', 'talnetant', 'Talnetant', 'talnetant', 'TALNETANT', 'TALNETANT', None, 'Talnetant', 'Talnetant', 'Talnetant', 'talnetant', 'TALNETANT', 'Talnetant', 'TALNETANT', 'TALNETANT', '(S)-3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide', '(S)-(-)-N-(a-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide', 'Talnetant', 'TALNETANT'] |
|---|
| Withdrawn Flag | False |
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| Orphan | 0 |
|---|
