IBD Research Resource Center

BioID	bio3153
Name	MIZACORAT
ChEMBL ID	CHEMBL4207852
Molecular Formula	C27H28F2N4O3
Molecular Weight	494.54
Molecular Weight (Monoisotopic)	494.2129
Type	Small molecule
Max Phase	Phase 2
Target ID	Tar12
Target Name	Toll-like receptor 9 (TLR9)
Synonyms	AZD 9567\|AZD-9567\|AZD9567\|MIZACORAT
Smiles	CC(C)[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2c(cnn2-c2ccc(=O)n(C)c2)c1)c1ccccc1
Inchi	InChI=1S/C27H28F2N4O3/c1-17(2)24(31-26(35)27(3,28)29)25(18-8-6-5-7-9-18)36-21-11-12-22-19(14-21)15-30-33(22)20-10-13-23(34)32(4)16-20/h5-17,24-25H,1-4H3,(H,31,35)/t24-,25+/m0/s1
Inchi Key	ZQFNDBISEYQVRR-LOSJGSFVSA-N
Molecular Species	NEUTRAL
Targets	14.0
Bioactivities	54.0
Np Likeness Score	-0.83
Records Key	['15; AZD9567', 'MIZACORAT', 'MIZACORAT', 'AZD9567', 'AZD9567']
Records Name	['2,2-difluoro-N-((1R,2S)-3-methyl-1-(1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-5-yloxy)-1-phenylbutan-2-yl)propanamide', 'MIZACORAT', 'MIZACORAT', '2,2-difluoro-N-((1R,2S)-3-methyl-1-((1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-5-yl)oxy)-1-phenylbutan-2-yl)propanamide', '2,2-difluoro-N-((1R,2S)-3-methyl-1-((1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-5-yl)oxy)-1-phenylbutan-2-yl)propanamide']
Withdrawn Flag	False
Orphan	0