| BioID | bio3310 |
|---|
| Name | AUMOLERTINIB |
|---|
| ChEMBL ID | CHEMBL4761468 |
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| Molecular Formula | C30H35N7O2 |
|---|
| Molecular Weight | 525.66 |
|---|
| Molecular Weight (Monoisotopic) | 525.2852 |
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| Type | Small molecule |
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| Max Phase | Phase 3 |
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| Target ID | Tar12 |
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| Target Name | Toll-like receptor 9 (TLR9) |
|---|
| Synonyms | ALMONERTINIB|AMEILE|AMEROL|AUMOLERTINIB|Ameile|Amerol|EGFR T790M INHIBITOR HS-10296|EQ-143|EQ143|HS 10296|HS-10206|HS-10296 |
|---|
| Smiles | C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C4CC4)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C |
|---|
| Inchi | InChI=1S/C30H35N7O2/c1-6-29(38)32-24-17-25(28(39-5)18-27(24)36(4)16-15-35(2)3)34-30-31-14-13-23(33-30)22-19-37(20-11-12-20)26-10-8-7-9-21(22)26/h6-10,13-14,17-20H,1,11-12,15-16H2,2-5H3,(H,32,38)(H,31,33,34) |
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| Inchi Key | DOEOECWDNSEFDN-UHFFFAOYSA-N |
|---|
| Molecular Species | BASE |
|---|
| Targets | 5.0 |
|---|
| Bioactivities | 23.0 |
|---|
| Np Likeness Score | -1.02 |
|---|
| Records Key | ['6b-1', 'AUMOLERTINIB', 'AUMOLERTINIB', 'AUMOLERTINIB'] |
|---|
| Records Name | ['N-(5-(4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-ylamino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide', 'AUMOLERTINIB', 'AUMOLERTINIB', 'AUMOLERTINIB'] |
|---|
| Withdrawn Flag | False |
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| Orphan | 0 |
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