| BioID | bio3366 |
|---|
| Name | RITLECITINIB |
|---|
| ChEMBL ID | CHEMBL4085457 |
|---|
| Molecular Formula | C15H19N5O |
|---|
| Molecular Weight | 285.35 |
|---|
| Molecular Weight (Monoisotopic) | 285.159 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 4 |
|---|
| Target ID | Tar18 |
|---|
| Target Name | Serine/threonine-protein kinase cot (COT) |
|---|
| Synonyms | PF-06651600|RITLECITINIB |
|---|
| Smiles | C=CC(=O)N1C[C@H](Nc2ncnc3[nH]ccc23)CC[C@@H]1C |
|---|
| Inchi | InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1 |
|---|
| Inchi Key | CBRJPFGIXUFMTM-WDEREUQCSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 34.0 |
|---|
| Bioactivities | 133.0 |
|---|
| Np Likeness Score | -0.84 |
|---|
| Records Key | ['PF-06651600', 'RITLECITINIB', 'PF-06651600; 6', '11', '23; PF-06651600', '8; PF-06651600', '3; PF-06651600', 'PF-06651600', '3; PF-06651600', 'PF-06651600', '7', 'COVC-0135627364', 'PF-06651600', '31', '11; PF-06651600', 'PF-06651600', '5; PF-06651600', '21'] |
|---|
| Records Name | ['PF-06651600', 'RITLECITINIB', '1-((2S,5R)-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-methylpiperidin-1-yl)prop-2-en-1-one', '1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-amino)-2-methylpiperidin-1-yl)prop-2-en-1-one', '1-((2S,5R)-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-methylpiperidin-1-yl)prop-2-en-1-one', '1-((2S,5R)-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-methylpiperidin-1-yl)prop-2-en-1-one', '1-((2S,5R)-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-methylpiperidin-1-yl)prop-2-en-1-one', '1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one', '1-((2S,5R)-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-methylpiperidin-1-yl)prop-2-en-1-one', 'PF-06651600', 'Ritlecitinib', 'PF-06651600', '1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one', 'Ritlecitinib', '1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one', 'Ritlecitinib', '1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one', 'Ritlecitinib'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
