| BioID | bio3375 |
|---|
| Name | RIPRETINIB |
|---|
| ChEMBL ID | CHEMBL4216467 |
|---|
| Molecular Formula | C24H21BrFN5O2 |
|---|
| Molecular Weight | 510.37 |
|---|
| Molecular Weight (Monoisotopic) | 509.0863 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 4 |
|---|
| Target ID | Tar18 |
|---|
| Target Name | Serine/threonine-protein kinase cot (COT) |
|---|
| Synonyms | DCC-2618|Qinlock|RIPRETINIB |
|---|
| Smiles | CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21 |
|---|
| Inchi | InChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33) |
|---|
| Inchi Key | CEFJVGZHQAGLHS-UHFFFAOYSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 6.0 |
|---|
| Bioactivities | 29.0 |
|---|
| Np Likeness Score | -1.53 |
|---|
| Records Key | ['4; DCC-2618', 'RIPRETINIB', 'RIPRETINIB', 'RIPRETINIB', 'RIPRETINIB', 'RIPRETINIB', 'Ripretinib', 'Ripretinib'] |
|---|
| Records Name | ['Ripretinib', 'RIPRETINIB', 'RIPRETINIB', 'RIPRETINIB', 'RIPRETINIB', 'RIPRETINIB', 'Ripretinib', 'Ripretinib'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 1 |
|---|
