| BioID | bio3395 |
|---|
| Name | FIBOFLAPON |
|---|
| ChEMBL ID | CHEMBL1922660 |
|---|
| Molecular Formula | C38H43N3O4S |
|---|
| Molecular Weight | 637.85 |
|---|
| Molecular Weight (Monoisotopic) | 637.2974 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 3 |
|---|
| Target ID | Tar18 |
|---|
| Target Name | Serine/threonine-protein kinase cot (COT) |
|---|
| Synonyms | AM-803|AM803|FIBOFLAPON|GSK-2190915|GSK2190915|GSK2190915B |
|---|
| Smiles | CCOc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)O)c(SC(C)(C)C)c4cc(OCc5ccc(C)cn5)ccc43)cc2)cn1 |
|---|
| Inchi | InChI=1S/C38H43N3O4S/c1-8-44-34-18-14-28(22-40-34)27-12-10-26(11-13-27)23-41-32-17-16-30(45-24-29-15-9-25(2)21-39-29)19-31(32)35(46-37(3,4)5)33(41)20-38(6,7)36(42)43/h9-19,21-22H,8,20,23-24H2,1-7H3,(H,42,43) |
|---|
| Inchi Key | DFQGDHBGRSTTHX-UHFFFAOYSA-N |
|---|
| Molecular Species | ACID |
|---|
| Targets | 20.0 |
|---|
| Bioactivities | 43.0 |
|---|
| Np Likeness Score | -0.8 |
|---|
| Records Key | ['BDBM125205', 'FIBOFLAPON', 'FIBOFLAPON', '11cc, AM803, GSK2190915', '5578', 'Fiboflapon sodium', 'COVC-1211281622'] |
|---|
| Records Name | ['US8772495, 2', 'FIBOFLAPON', 'FIBOFLAPON', '3-[3-tert-Butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid', None, 'Fiboflapon sodium', 'GSK2190915'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
