IBD Research Resource Center

BioID	bio3425
Name	ZIMLOVISERTIB
ChEMBL ID	CHEMBL4081711
Molecular Formula	C18H20FN3O4
Molecular Weight	361.37
Molecular Weight (Monoisotopic)	361.1438
Type	Small molecule
Max Phase	Phase 2
Target ID	Tar18
Target Name	Serine/threonine-protein kinase cot (COT)
Synonyms	PF 06650833\|PF-06650833\|ZIMLOVISERTIB
Smiles	CC[C@@H]1[C@H](F)C(=O)N[C@@H]1COc1nccc2cc(C(N)=O)c(OC)cc12
Inchi	InChI=1S/C18H20FN3O4/c1-3-10-13(22-17(24)15(10)19)8-26-18-11-7-14(25-2)12(16(20)23)6-9(11)4-5-21-18/h4-7,10,13,15H,3,8H2,1-2H3,(H2,20,23)(H,22,24)/t10-,13+,15-/m0/s1
Inchi Key	JKDGKIBAOAFRPJ-ZBINZKHDSA-N
Molecular Species	NEUTRAL
Targets	397.0
Bioactivities	2182.0
Np Likeness Score	-0.02
Records Key	['PF-06650833', 'COVC-0135603694', '40; PF-06650833', 'PF06650833', 'ZIMLOVISERTIB', 'PF06650833', 'EUB0000639a', 'ZIMLOVISERTIB', 'EUB0000639a', 'EUB0000639a', '1; PF-06650833', 'EUB0000639a', 'PF-06650833', 'EOS100210', 'EUB0000639a', 'EUB0000639a', 'EUB0000639a']
Records Name	['1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide', 'PF-06650833', '1-(((2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide', 'PF06650833', 'ZIMLOVISERTIB', 'PF06650833', 'PF-06650833', 'ZIMLOVISERTIB', 'PF-06650833', 'PF-06650833', 'Zimlovisertib', 'PF-06650833', '1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide', 'PF-06650833', 'PF-06650833', 'PF-06650833', 'PF-06650833']
Withdrawn Flag	False
Orphan	0