| BioID | bio3465 |
|---|
| Name | EFIPLADIB |
|---|
| ChEMBL ID | CHEMBL272342 |
|---|
| Molecular Formula | C40H35Cl3N2O4S |
|---|
| Molecular Weight | 746.16 |
|---|
| Molecular Weight (Monoisotopic) | 744.1383 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 2 |
|---|
| Target ID | Tar18 |
|---|
| Target Name | Serine/threonine-protein kinase cot (COT) |
|---|
| Synonyms | EFIPLADIB|PLA-902 |
|---|
| Smiles | O=C(O)c1ccc(CCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)c(Cl)c3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 |
|---|
| Inchi | InChI=1S/C40H35Cl3N2O4S/c41-32-19-21-37-34(25-32)33(13-7-8-27-14-17-31(18-15-27)40(46)47)38(22-23-44-50(48,49)26-28-16-20-35(42)36(43)24-28)45(37)39(29-9-3-1-4-10-29)30-11-5-2-6-12-30/h1-6,9-12,14-21,24-25,39,44H,7-8,13,22-23,26H2,(H,46,47) |
|---|
| Inchi Key | HIZOPJQOPKRKFM-UHFFFAOYSA-N |
|---|
| Molecular Species | ACID |
|---|
| Targets | 15.0 |
|---|
| Bioactivities | 57.0 |
|---|
| Np Likeness Score | -0.9 |
|---|
| Records Key | ['Efipladib', '2, efipladib', '3', '111', 'EFIPLADIB', '1'] |
|---|
| Records Name | ['Efipladib', '4-(3-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophenyl)methylsulfonamido)ethyl)-1H-indol-3-yl)propyl)benzoic acid', '4-(3-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophenyl)methylsulfonamido)ethyl)-1H-indol-3-yl)propyl)benzoic acid', '4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid', 'EFIPLADIB', 'Efipladib'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
