| BioID | bio3521 |
|---|
| Name | DARIZMETINIB |
|---|
| ChEMBL ID | CHEMBL4795907 |
|---|
| Molecular Formula | C21H17F2N5O3S |
|---|
| Molecular Weight | 457.46 |
|---|
| Molecular Weight (Monoisotopic) | 457.102 |
|---|
| Type | Small molecule |
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| Max Phase | Phase 2 |
|---|
| Target ID | Tar18 |
|---|
| Target Name | Serine/threonine-protein kinase cot (COT) |
|---|
| Synonyms | DARIZMETINIB |
|---|
| Smiles | CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4ccncc4)cc23)c1F |
|---|
| Inchi | InChI=1S/C21H17F2N5O3S/c1-2-9-32(30,31)28-19-16(22)4-3-14(17(19)23)20(29)18-15-10-13(11-25-21(15)27-26-18)12-5-7-24-8-6-12/h3-8,10-11,28H,2,9H2,1H3,(H,25,26,27) |
|---|
| Inchi Key | WBNMARNYIFMNEP-UHFFFAOYSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 2.0 |
|---|
| Bioactivities | 7.0 |
|---|
| Np Likeness Score | -1.54 |
|---|
| Records Key | ['Exp 63', 'DARIZMETINIB'] |
|---|
| Records Name | ['N-(2,6-difluoro-3-(5-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl)phenyl)propane-1-sulfonamide', 'DARIZMETINIB'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
