| BioID | bio3527 |
|---|
| Name | DIACYLGLYCEROL KINASE INHIBITOR II |
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| ChEMBL ID | CHEMBL261131 |
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| Molecular Formula | C28H25F2N3OS |
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| Molecular Weight | 489.59 |
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| Molecular Weight (Monoisotopic) | 489.1686 |
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| Type | Small molecule |
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| Max Phase | -- |
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| Target ID | Tar18 |
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| Target Name | Serine/threonine-protein kinase cot (COT) |
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| Synonyms | Diacylglycerol Kinase Inhibitor Ii |
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| Smiles | O=c1c2ccccc2[nH]c(=S)n1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 |
|---|
| Inchi | InChI=1S/C28H25F2N3OS/c29-22-9-5-19(6-10-22)26(20-7-11-23(30)12-8-20)21-13-15-32(16-14-21)17-18-33-27(34)24-3-1-2-4-25(24)31-28(33)35/h1-12H,13-18H2,(H,31,35) |
|---|
| Inchi Key | ZCNBZFRECRPCKU-UHFFFAOYSA-N |
|---|
| Molecular Species | NEUTRAL |
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| Targets | 269.0 |
|---|
| Bioactivities | 566.0 |
|---|
| Np Likeness Score | -1.06 |
|---|
| Records Key | ['R-59949', 'Diacylglycerol Kinase Inhibitor II', 'K00032, R59949', 'SID855913', 'NCGC00093804-01', 'K00032', 'R59949', 'R59949'] |
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| Records Name | ['R-59949', '3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one', '3-{2-[4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl]ethyl}-2,3-dihydro-2-thioxo-4(1H)quinazolinone', 'SID855913', 'Diacylglycerol Kinase Inhibitor II', 'K00032', '3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one', '3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one'] |
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| Withdrawn Flag | False |
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| Orphan | -1 |
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