| BioID | bio3540 |
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| Name | SELONSERTIB |
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| ChEMBL ID | CHEMBL3916717 |
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| Molecular Formula | C24H24FN7O |
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| Molecular Weight | 445.5 |
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| Molecular Weight (Monoisotopic) | 445.2026 |
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| Type | Small molecule |
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| Max Phase | Phase 3 |
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| Target ID | Tar18 |
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| Target Name | Serine/threonine-protein kinase cot (COT) |
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| Synonyms | GS-4997|SELONSERTIB |
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| Smiles | Cc1cc(F)c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)cc1-n1cnc(C2CC2)c1 |
|---|
| Inchi | InChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33) |
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| Inchi Key | YIDDLAAKOYYGJG-UHFFFAOYSA-N |
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| Molecular Species | NEUTRAL |
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| Targets | 335.0 |
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| Bioactivities | 728.0 |
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| Np Likeness Score | -1.79 |
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| Records Key | ['SELONSERTIB', 'selonsertib', '4; GS-4997', '3', 'COVC-3370899793', '4', '2; GS-4997', 'selonsertib', 'SELONSERTIB', '2; GS-4997', '1; GS-4997', '6; GS-4997', '2; GS-4997', 'EUB0000695a', '2', 'EOS101171', 'GS-4997', 'EUB0000695a', 'EUB0000695a', 'EUB0000695a', 'EUB0000695a', 'EUB0000695a', 'EUB0000695a'] |
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| Records Name | ['SELONSERTIB', 'selonsertib', 'Selonsertib', '5-(4-cyclopropylimidazol-1-yl)-2-fluoro-N-[6-(4-isopropyl-1,2,4-triazol-3-yl)-2-pyridyl]-4-methyl-benzamide', 'SELONSERTIB HYDROCHLORIDE', '5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide', 'Selonsertib', 'selonsertib', 'SELONSERTIB', '5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide', '5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide', '5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide', '5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide', 'Selonsertib', 'Selonsertib', 'selonsertib', 'Selonsertib', 'Selonsertib', 'Selonsertib', 'Selonsertib', 'Selonsertib', 'Selonsertib', 'Selonsertib'] |
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| Withdrawn Flag | False |
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| Orphan | 0 |
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