IBD Research Resource Center

BioID	bio3550
Name	GLESATINIB
ChEMBL ID	CHEMBL3989914
Molecular Formula	C31H27F2N5O3S2
Molecular Weight	619.72
Molecular Weight (Monoisotopic)	619.1523
Type	Small molecule
Max Phase	Phase 2
Target ID	Tar18
Target Name	Serine/threonine-protein kinase cot (COT)
Synonyms	GLESATINIB\|MG-90265\|MG-90265X\|MG90265\|MG90265H9\|MG90265X\|MG90265gly\|MGCD-265\|MGCD265
Smiles	COCCNCc1ccc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccc(F)cc5)cc4F)c3s2)nc1
Inchi	InChI=1S/C31H27F2N5O3S2/c1-40-13-12-34-17-20-4-8-24(36-18-20)28-16-25-30(43-28)27(10-11-35-25)41-26-9-7-22(15-23(26)33)37-31(42)38-29(39)14-19-2-5-21(32)6-3-19/h2-11,15-16,18,34H,12-14,17H2,1H3,(H2,37,38,39,42)
Inchi Key	YRCHYHRCBXNYNU-UHFFFAOYSA-N
Molecular Species	NEUTRAL
Targets	301.0
Bioactivities	316.0
Np Likeness Score	-1.77
Records Key	['MGCD-265', 'GLESATINIB', 'MGCD265', '4; MGCD265', 'MGCD-265', 'MGCD-265', 'MGCD-265', 'GLESATINIB', 'MGCD-265', 'COVC-3893361119', '84']
Records Name	['MGCD-265', 'GLESATINIB', 'N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide', 'N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide', 'MGCD-265', 'MGCD-265', 'MGCD-265', 'GLESATINIB', 'N-(4-(2-(1-ethyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide', 'MGCD-265', 'Glesatinib']
Withdrawn Flag	False
Orphan	0