| BioID | bio3553 |
|---|
| Name | GILTERITINIB |
|---|
| ChEMBL ID | CHEMBL3301622 |
|---|
| Molecular Formula | C29H44N8O3 |
|---|
| Molecular Weight | 552.72 |
|---|
| Molecular Weight (Monoisotopic) | 552.3536 |
|---|
| Type | Small molecule |
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| Max Phase | Phase 4 |
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| Target ID | Tar18 |
|---|
| Target Name | Serine/threonine-protein kinase cot (COT) |
|---|
| Synonyms | ASP-2215|ASP2215|GILTERITINIB|Gilteritinib |
|---|
| Smiles | CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(OC)c2)nc1NC1CCOCC1 |
|---|
| Inchi | InChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34) |
|---|
| Inchi Key | GYQYAJJFPNQOOW-UHFFFAOYSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 335.0 |
|---|
| Bioactivities | 430.0 |
|---|
| Np Likeness Score | -1.1 |
|---|
| Records Key | ['Gilteritinib', 'Ex 547', 'GILTERITINIB', 'GILTERITINIB', '9; ASP2215', 'Gilteritinib (ASP2215)', 'Gilteritinib', 'BDBM144315', 'GILTERITINIB', '5; ASP2215', 'Gilteritinib', 'GILTERITINIB', '20; ASP2215', 'Gilteritinib', 'COVC-3907659796', 'Gilteritinib', '3e', 'Gilteritinib', 'Gilteritinib', '1', 'Gilteritinib', '8', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'ASP-2215', '20', 'gilteritinib', '7; ASP2215', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib'] |
|---|
| Records Name | ['Gilteritinib', '6-ethyl-3-(3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenylamino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide', 'GILTERITINIB', 'GILTERITINIB', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'US8969336, 547::US8969336, 577', 'GILTERITINIB', 'Gilteritinib', 'Gilteritinib', 'GILTERITINIB', 'Gilteritinib', 'Gilteritinib', 'GILTERITINIB', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib', 'Gilteritinib'] |
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| Withdrawn Flag | False |
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| Orphan | 1 |
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