| BioID | bio3567 |
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| Name | OMIPALISIB |
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| ChEMBL ID | CHEMBL1236962 |
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| Molecular Formula | C25H17F2N5O3S |
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| Molecular Weight | 505.51 |
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| Molecular Weight (Monoisotopic) | 505.102 |
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| Type | Small molecule |
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| Max Phase | Phase 2 |
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| Target ID | Tar18 |
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| Target Name | Serine/threonine-protein kinase cot (COT) |
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| Synonyms | GSK-2126458|GSK2126458|OMIPALISIB|Omipalisib |
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| Smiles | COc1ncc(-c2ccc3nccc(-c4ccnnc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F |
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| Inchi | InChI=1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3 |
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| Inchi Key | CGBJSGAELGCMKE-UHFFFAOYSA-N |
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| Molecular Species | NEUTRAL |
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| Targets | 328.0 |
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| Bioactivities | 1474.0 |
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| Np Likeness Score | -1.41 |
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| Records Key | ['GSK2126458', 'OMIPALISIB', 'Omipalisib', 'OMIPALISIB', 'Omipalisib (GSK2126458; GSK458)', 'OMIPALISIB (GSK2126458, GSK458)', 'GSK2126458', '58, GSK2126458', 'EUB0000691a', 'SID137275909', 'OMIPALISIB', '5599', '4; GSK-2126458', 'OMIPALISIB', 'GSK2126458', 'Omipalisib (GSK2126458; GSK458)', '3', 'GSK-2126458', 'Omipalisib', 'Omipalisib (GSK2126458; GSK458)', 'EUB0000691a', '1; GSK2126458', 'EUB0000691a', 'EUB0000691a', 'GSK; GSK-2126458', 'EOS101801', 'EOS101801', '117; GSK458', 'EUB0000691a', '3; GSK2126458', 'Omipalisib', '8; GSK2126458', 'EOS101801'] |
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| Records Name | ['2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', 'OMIPALISIB', 'Omipalisib', 'OMIPALISIB', 'Omipalisib (GSK2126458; GSK458)', 'OMIPALISIB (GSK2126458, GSK458)', '2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', '2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', 'Omipalisib', 'SID137275909', 'OMIPALISIB', None, '2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', 'OMIPALISIB', '2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', 'Omipalisib (GSK2126458; GSK458)', 'Omipalisib', '2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', 'Omipalisib', 'Omipalisib (GSK2126458; GSK458)', 'Omipalisib', 'Omipalisib', 'Omipalisib', 'Omipalisib', 'NA', 'OMIPALISIB', 'OMIPALISIB', 'Omipalisib', 'Omipalisib', '2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide', 'Omipalisib', 'Omipalisib', 'OMIPALISIB'] |
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| Withdrawn Flag | False |
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| Orphan | 0 |
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