IBD Research Resource Center

BioID	bio44684
Name	NAVOXIMOD
ChEMBL ID	CHEMBL3989951
Molecular Formula	C18H21FN2O2
Molecular Weight	316.38
Molecular Weight (Monoisotopic)	316.1587
Type	Small molecule
Max Phase	Phase 2
Target ID	Tar10
Target Name	P2X purinoceptor 7 (P2RX7)
Synonyms	GDC-0919\|IDO-IN-7\|NAVOXIMOD\|NLG-919\|NLG919\|RG-6078\|RG6078\|RO-7077339\|RO7077339\|RO7077339-001
Smiles	O[C@H](C[C@H]1c2c(F)cccc2-c2cncn21)[C@H]1CC[C@H](O)CC1
Inchi	InChI=1S/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11-,12-,15-,17+/m0/s1
Inchi Key	YGACXVRLDHEXKY-WXRXAMBDSA-N
Molecular Species	NEUTRAL
Targets	17.0
Bioactivities	126.0
Np Likeness Score	0.05
Records Key	['NAVOXIMOD', 'NLG-919', '15; NLG919', 'GDC-0919', 'NAVOXIMOD', 'NLG-919', '3; GDC-0919', 'Navoximod', 'Navoximod', '1', 'Navoximod', 'GDC-0919', 'NLG-919']
Records Name	['NAVOXIMOD', '(1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol', 'Navoximod', '4-[(1R)-2-[(5S)-6-fluoro-5H-imidazo[1,5-b]isoindol-5-yl]-1-hydroxy-ethyl]cyclohexanol', 'NAVOXIMOD', 'Navoximod; (1R,4r)-4-((R)-2-((S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol', 'Navoximod', 'Navoximod', 'Navoximod', 'Navoximod', 'Navoximod', 'Navoximod; (1r,4r)-4-((R)-2-((S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol', 'Navoximod']
Withdrawn Flag	False
Orphan	0