Trial Details

NOT_YET_RECRUITING
Basic Information
Clinical ID c198
Identifier NCT06986382
Trial Title Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn Disease
Trial URL Visit Original Page
Study Information
Study Results

NO
Conditions Crohn Disease
Interventions DEVICE: CliniMACS® TCR α/β Reagent Kit and CliniMACS® CD19 System|DRUG: Prednisone/Methylprenisolone|DRUG: Palifermin|DRUG: ATG|DRUG: Clofarabine|DRUG: Melphalan|RADIATION: Total Body Irradiation|DRUG: Rituximab
Participant Information
Sponsor Stanford University
City Palo Alto
Country/Region United States
Enrollment Criteria
Sex Requirement ALL
Age Requirement CHILD, ADULT
Study Design
Study Type INTERVENTIONAL
Phase PHASE1|PHASE2
Time Information
Start Date 2025-07
Primary Completion Date 2037-07
Completion Date 2040-07