Trial Details

Not Recruiting
Basic Information
Clinical ID c1987
Identifier ChiCTR2500098333
Trial Title A Phase III, Multicenter, Double-Blind, Placebo-Controlled, Treat-Through Study To Assess The Efficacy And Safety Of Induction And Maintenance Therapy With RO7790121 In Patients With Moderately To Severely Active Crohn's Disease
Trial URL Visit Original Page
Study Information
Study Results

No results available
Conditions CD is a chronic, progressive inflammatory disease of the gastrointestinal tract, characterized by periods of relapse and remission, which can ultimately lead to bowel damage and disability. Most patients present with an inflammatory phenotype, but over time, uncontrolled inflammation can lead to complications such as fibrotic strictures, fistula formation, or intestinal neoplasia (Torres et al. 2
Interventions Test group 1:500 mg IV at weeks 0, 2, 6, and 10, followed by 450mg SC every 4 weeks from week 12 to week 52 (Q4W);Test group 2:500 mg IV at weeks 0, 2, 6, and 10, followed by 150 mg SCQ4W from week 12 to week 52;Placebo group:Placebo IV at weeks 0, 2, 6, and 10, followed by placebo SC Q4W from week 12 to week 52;
Participant Information
Sponsor Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
City -
Country/Region China
Enrollment Criteria
Sex Requirement ALL
Age Requirement ADULT, ELDER, OLDER_ADULT, TEENAGER
Study Design
Study Type Interventional study
Phase Not Available
Time Information
Start Date 2025-04-24
Primary Completion Date -
Completion Date -