| Interventions |
We will be following individuals with an ileoanal pouch over 18 months to identify if dietary factors or psychological stress are environmental factors that can predict the onset or worsening of pouchitis. Participants will complete 3-day food diaries, complete a series of online questionnaires related to their pouch function and stress as well as collecting biological samples. Data will be collected online every 6 months, and biological samples will be collected at home and posted back to researchers. Secondly, from the data we collected, we will be assessing how useful faecal calprotectin can be used as a prognostic marker for the development or worsening of pouchitis. In order to achieve this, we will be collecting information about what participants eat, how their pouch functions, their stress levels and psychological wellbeing. Faecal calprotectin in their stools will be collected and hair samples as a retrospective way of looking at the stress hormone, cortisol to identify chronic stress. Dietary intake will be assessed on its overall healthfulness and used to find underlying relationships with pouchitis. |