| Interventions |
This study involves no intervention. The study team does not provide SARS-CoV-2 vaccination. The researchers only observe the immune response to SARS-CoV-2 vaccination. The vaccination itself is carried out through the national vaccination program. The SARS-CoV-2 vaccination is not performed at the study site. The researchers expect that the majority of patients will be vaccinated by their general practitioners. They bear no responsibility for the administration of the vaccine and any associated complications. Throughout the study, all necessary data concerning the SARS-CoV-2 vaccination are obtained from a survey. The study consists of a total of three visits in which the patients will fill out a questionnaire and a blood sample is collected for detection of antibodies against SARS-CoV-2, total immunoglobulin G levels, and various other immunological parameters. The initial blood sample also includes an examination of complete blood count and basic biochemistry to determine the activity of IBD or AIH, and an examination of the level of 25-hydroxyvitamin D, which plays an important role in immune functions. The initial visit and inclusion in the study must take place within 1 month before the start of SARS-CoV-2 vaccination, the second visit is scheduled 1 month after the end of vaccination and the third and last visit is scheduled 6 months after the end of vaccination. |