Drug Targets List

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Drug Targets List

Target ID CID Compound Name Gene ID Gene Name Species PubMed IDs Action Details
dt91 2353 Berberine 7150 TOP1 Homo sapiens (human) 23747414 Berberine results in decreased activity of TOP1 protein Details
dt92 2353 Berberine 7153 TOP2A Homo sapiens (human) 23747414 TOP2A protein affects the susceptibility to berberine|top2a protein affects the reaction [berberine results in increased expression of H2AX protein modified form] Details
dt93 2353 Berberine 7157 TP53 Homo sapiens (human) 26712469 Berberine results in increased phosphorylation of and results in increased acetylation of TP53 protein|[berberine co-treated with niacinamide] results in increased expression of and results in increased acetylation of TP53 protein Details
dt94 2353 Berberine 7157 TP53 Homo sapiens (human) 20656010 Berberine results in increased expression of TP53 mrna|berberine results in increased expression of TP53 protein Details
dt95 2353 Berberine 7186 TRAF2 Mus musculus (house mouse) 30240693 Berberine inhibits the reaction [[lipopolysaccharide, escherichia coli O111 B4 co-treated with TNF protein] results in increased secretion of TRAF2 protein]|berberine inhibits the reaction [[lipopolysaccharide, escherichia coli O111 B4 co-treated with TNF Details
dt96 2353 Berberine 6737 TRIM21 Homo sapiens (human) 36822301 Berberine promotes the reaction [IGF2BP3 protein binds to TRIM21 protein] Details
dt97 2353 Berberine 100131187 TSTD1 Homo sapiens (human) 27311644 Berberine results in increased expression of TSTD1 mRNA Details
dt98 2353 Berberine 7319 UBE2A Homo sapiens (human) 27311644 Berberine results in decreased expression of UBE2A mRNA Details
dt99 2353 Berberine 7320 UBE2B Homo sapiens (human) 27311644 Berberine results in decreased expression of UBE2B mRNA Details
dt100 2519 Caffeine 5142 PDE4B Homo sapiens (human) -- -- Details