| Target ID: | dt1377 |
|---|---|
| CID: | 5311066 |
| Compound Name: | Desonide |
| Gene ID: | 367 |
| Gene Name: | AR |
| Species: | Homo sapiens (human) |
| PubMed IDs: | -- |
| Action: | -- |
Knowledge Graph
| Target ID | CID | Compound Name | Gene ID | Gene Name | Species | Action | |
|---|---|---|---|---|---|---|---|
| dt1046 | 23680530 | Methylprednisolone Sodium Succinate | 367 | AR | Homo sapiens (human) | -- | Details |
| dt1048 | 23694214 | Hydrocortisone Sodium Succinate | 367 | AR | Homo sapiens (human) | -- | Details |
| dt449 | 12456 | Berberine Chloride | 367 | AR | Homo sapiens (human) | -- | Details |
| dt518 | 41684 | Nitazoxanide | 367 | AR | Homo sapiens (human) | Nitazoxanide binds to and results in decreased activity of AR protein | Details |
| dt579 | 134018 | Febuxostat | 367 | AR | Homo sapiens (human) | -- | Details |
| dt736 | 5280795 | Cholecalciferol | 367 | AR | Homo sapiens (human) | -- | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug196 | Desonide | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio150857 | CHEMBL730 | Small molecule | NITROGLYCERIN | 227.08 | C3H5N3O9 | NEUTRAL | Details |
| bio150858 | CHEMBL1236936 | Small molecule | CINACIGUAT | 565.71 | C36H39NO5 | ZWITTERION | Details |
| bio150859 | CHEMBL1088752 | Small molecule | LOSMAPIMOD | 383.47 | C22H26FN3O2 | NEUTRAL | Details |
| bio150860 | CHEMBL1200332 | Small molecule | PROTRIPTYLINE HYDROCHLORIDE | 299.85 | C19H22ClN | BASE | Details |
| bio150861 | CHEMBL4650335 | Protein | NENDRATAREOTIDE UZATANSINE | 1786.58 | C83H109ClN14O20S4 | -- | Details |
| bio150862 | CHEMBL2108175 | Unknown | ANTIHEMOPHILIC FACTOR | -- | -- | -- | Details |
| bio150863 | CHEMBL13209 | Small molecule | NITRAZEPAM | 281.27 | C15H11N3O3 | NEUTRAL | Details |
| bio150864 | CHEMBL3987016 | Small molecule | MIVEBRESIB | 459.47 | C22H19F2N3O4S | NEUTRAL | Details |
| bio150865 | CHEMBL495 | Small molecule | ALPROSTADIL | 354.49 | C20H34O5 | ACID | Details |
| bio150866 | CHEMBL1201794 | Small molecule | RIBOFLAVIN 5'-PHOSPHATE | 456.35 | C17H21N4O9P | ACID | Details |
| Disease ID | Disease Name | Definition | Mechanism | |
|---|---|---|---|---|
| 1.0 | Crohn's disease | An intestinal disease that involves inflammation located_in… | Crohn's disease is a relapsing systemic inflammatory diseas… | Details |
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| S01 | Anti-inflammatory | inflammatory | 5-Aminosalicylates (5-ASAs); corticosteroids | Crohn's disease and ulcerative colitis are the two main com… | Details |
| S02 | Immunosuppression | Classic immunosuppressive drugs | azathioprine; 6-mercaptopurine; methotrexate; ciclosporin-A; tacrolimus | Ciclosporin-A and tacrolimus bind to specific intracellular… | Details |
| S04 | T-cell homing and retention | T-cell trafficking | vedolizumab; anti-MAdCAM1 antibodies ; etrolizumab | Inhibition of the interaction between α4β7 integrins on T c… | Details |