| Target ID: | dt28 |
|---|---|
| CID: | 864 |
| Compound Name: | Thioctic Acid |
| Gene ID: | 5243 |
| Gene Name: | ABCB1 |
| Species: | Mus musculus (house mouse) |
| PubMed IDs: | 29128272 |
| Action: | [thioctic acid co-treated with saxitoxin] affects the activity of ABCB1 protein |
Knowledge Graph
| Target ID | CID | Compound Name | Gene ID | Gene Name | Species | Action | |
|---|---|---|---|---|---|---|---|
| dt1137 | 54671203 | Doxycycline | 5243 | ABCB1 | Homo sapiens (human) | Doxycycline results in decreased expression of ABCB1 protein | Details |
| dt129 | 2812 | Clotrimazole | 5243 | ABCB1 | Cyprinus carpio (common carp) | Clotrimazole results in decreased expression of ABCB1 mRNA | Details |
| dt130 | 2812 | Clotrimazole | 5243 | ABCB1 | Homo sapiens (human) | Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of doxorubicin]|clotrimazole binds to ABCB1 protein | Details |
| dt131 | 2812 | Clotrimazole | 5243 | ABCB1 | Homo sapiens (human) | Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon] | Details |
| dt1319 | 2756 | Cimetidine | 5243 | ABCB1 | Homo sapiens (human) | Substrate|Inducer | Details |
| dt132 | 2812 | Clotrimazole | 5243 | ABCB1 | Homo sapiens (human) | Clotrimazole results in increased expression of ABCB1 protein | Details |
| dt164 | 3365 | Fluconazole | 5243 | ABCB1 | Homo sapiens (human) | Inhibitor | Details |
| dt170 | 3446 | Gabapentin | 5243 | ABCB1 | Homo sapiens (human) | Gabapentin results in decreased activity of ABCB1 protein | Details |
| dt299 | 4594 | Omeprazole | 5243 | ABCB1 | Homo sapiens (human) | -- | Details |
| dt320 | 4740 | Pentoxifylline | 5243 | ABCB1 | Homo sapiens (human) | [pentoxifylline co-treated with doxorubicin] results in decreased expression of ABCB1 protein|pentoxifylline results in decreased expression of ABCB1 protein | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug4 | Alpha-Lipoic Acid | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio183760 | CHEMBL4067549 | Small molecule | ULECACICLIB | 496.66 | C25H33FN8S | NEUTRAL | Details |
| bio183761 | CHEMBL4442620 | Small molecule | RONICICLIB | 430.45 | C18H21F3N4O3S | NEUTRAL | Details |
| bio183762 | CHEMBL1944698 | Small molecule | ZOTIRACICLIB | 372.47 | C23H24N4O | NEUTRAL | Details |
| bio183763 | CHEMBL5201870 | Small molecule | TAGTOCICLIB | 404.47 | C19H28N6O4 | NEUTRAL | Details |
| bio183764 | CHEMBL1206245 | Small molecule | BRICICLIB | 474.42 | C19H23O10PS | ACID | Details |
| bio183765 | CHEMBL1383 | Small molecule | DDA-TRIPHOSPHATE | 475.18 | C10H16N5O11P3 | ACID | Details |
| bio183766 | CHEMBL1160964 | Small molecule | -- | 476.17 | C9H15N6O11P3 | ACID | Details |
| bio183767 | CHEMBL5095084 | Small molecule | TANUXICICLIB | 312.31 | C15H13FN6O | NEUTRAL | Details |
| bio183768 | CHEMBL131890 | Small molecule | ATPGAMMAS | 523.25 | C10H16N5O12P3S | ACID | Details |
| bio183769 | CHEMBL374931 | Small molecule | -- | 521.21 | C11H18N5O13P3 | ACID | Details |
| Disease ID | Disease Name | Definition | Mechanism | |
|---|---|---|---|---|
| No data available | ||||
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||