| Target ID: | dt31 |
|---|---|
| CID: | 864 |
| Compound Name: | Thioctic Acid |
| Gene ID: | 1636 |
| Gene Name: | ACE |
| Species: | Rattus norvegicus (Norway rat) |
| PubMed IDs: | 26518973 |
| Action: | Thioctic acid inhibits the reaction [sodium chloride, dietary results in increased expression of ACE] |
Knowledge Graph
| Target ID | CID | Compound Name | Gene ID | Gene Name | Species | Action | |
|---|---|---|---|---|---|---|---|
| dt215 | 3715 | Indomethacin | 1636 | ACE | Homo sapiens (human) | -- | Details |
| dt30 | 864 | Thioctic Acid | 1636 | ACE | Mus musculus (house mouse) | Thioctic acid affects the reaction [dietary fats affects the activity of ACE protein]|thioctic acid affects the reaction [dietary fats affects the expression of ACE mrna] | Details |
| dt305 | 4595 | Ondansetron | 1636 | ACE | Rattus norvegicus (Norway rat) | Ondansetron inhibits the reaction [cisplatin results in increased expression of ACE protein] | Details |
| dt628 | 448281 | Mln-4760 | 1636 | ACE | Homo sapiens (human) | 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid results in decreased activity of ACE protein | Details |
| dt629 | 448281 | Mln-4760 | 1636 | ACE | Mus musculus (house mouse) | 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [angiotensin I (1-7) inhibits the reaction [AGT protein results in increased expression of ACE mrna]]|2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3 | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug4 | Alpha-Lipoic Acid | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| bio188438 | CHEMBL730 | Small molecule | NITROGLYCERIN | 227.08 | C3H5N3O9 | NEUTRAL | Details |
| bio188439 | CHEMBL878 | Small molecule | METOLAZONE | 365.84 | C16H16ClN3O3S | NEUTRAL | Details |
| bio188440 | CHEMBL1079604 | Small molecule | METAXALONE | 221.26 | C12H15NO3 | NEUTRAL | Details |
| bio188441 | CHEMBL1200399 | Small molecule | BUSPIRONE HYDROCHLORIDE | 421.97 | C21H32ClN5O2 | NEUTRAL | Details |
| bio188442 | CHEMBL1200436 | Small molecule | OXANDROLONE | 306.45 | C19H30O3 | NEUTRAL | Details |
| bio188443 | CHEMBL5095183 | Small molecule | IMLUNESTRANT | 524.51 | C29H24F4N2O3 | NEUTRAL | Details |
| bio188444 | CHEMBL1200332 | Small molecule | PROTRIPTYLINE HYDROCHLORIDE | 299.85 | C19H22ClN | BASE | Details |
| bio188445 | CHEMBL3707377 | Small molecule | SEGESTERONE ACETATE | 370.49 | C23H30O4 | NEUTRAL | Details |
| bio188446 | CHEMBL5314602 | Small molecule | HYPERICIN SODIUM | 526.43 | C30H15NaO8 | NEUTRAL | Details |
| bio188447 | CHEMBL603 | Small molecule | ZAFIRLUKAST | 575.69 | C31H33N3O6S | ACID | Details |
| Disease ID | Disease Name | Definition | Mechanism | |
|---|---|---|---|---|
| No data available | ||||
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||