| Target ID: | dt633 |
|---|---|
| CID: | 448281 |
| Compound Name: | Mln-4760 |
| Gene ID: | 3553 |
| Gene Name: | IL1B |
| Species: | Rattus norvegicus (Norway rat) |
| PubMed IDs: | 27302421 |
| Action: | SB 203580 inhibits the reaction [2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of IL1B protein]]]|2 |
Knowledge Graph
| Target ID | CID | Compound Name | Gene ID | Gene Name | Species | Action | |
|---|---|---|---|---|---|---|---|
| dt1140 | 54675783 | Minocycline | 3553 | IL1B | Homo sapiens (human) | Modulator | Details |
| dt45 | 896 | Melatonin | 3553 | IL1B | Homo sapiens (human) | -- | Details |
| dt946 | 9887712 | Dapagliflozin | 3553 | IL1B | Rattus norvegicus (Norway rat) | [dapagliflozin co-treated with atorvastatin] inhibits the reaction [[dietary fats co-treated with fructose] results in increased expression of IL1B protein] | Details |
| dt947 | 9887712 | Dapagliflozin | 3553 | IL1B | Rattus norvegicus (Norway rat) | Dapagliflozin inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein]|[thapsigargin co-treated with dapagliflozin] inhibits the reaction [IL1B protein results in increased expression of BAX protein]|dapagliflozin inhibits t | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug74 | ORE1001 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
| Disease ID | Disease Name | Definition | Mechanism | |
|---|---|---|---|---|
| No data available | ||||
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||