| Target ID: | dt853 |
|---|---|
| CID: | 5479530 |
| Compound Name: | Ceftriaxone |
| Gene ID: | 7124 |
| Gene Name: | TNF |
| Species: | Rattus norvegicus (Norway rat) |
| PubMed IDs: | 25053526 |
| Action: | Ropinirole promotes the reaction [ceftriaxone inhibits the reaction [1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]]|ceftriaxone inhibits the reaction [1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in i |
Knowledge Graph
| Target ID | CID | Compound Name | Gene ID | Gene Name | Species | Action | |
|---|---|---|---|---|---|---|---|
| dt268 | 4192 | Midazolam | 7124 | TNF | Mus musculus (house mouse) | NFIL3 protein affects the reaction [jujuboside A affects the reaction [[midazolam co-treated with lipopolysaccharides] affects the expression of TNF protein]]|jujuboside A affects the reaction [[midazolam co-treated with lipopolysaccharides] affects the e | Details |
| dt301 | 4594 | Omeprazole | 7124 | TNF | Homo sapiens (human) | -- | Details |
| dt357 | 5426 | Thalidomide | 7124 | TNF | Homo sapiens (human) | -- | Details |
| dt626 | 448281 | Mln-4760 | 7124 | TNF | Rattus norvegicus (Norway rat) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in i | Details |
| dt90 | 2353 | Berberine | 7124 | TNF | Rattus norvegicus (Norway rat) | Berberine inhibits the reaction [mercuric chloride results in increased expression of TNF protein] | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug100 | Ceftriaxone | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
| Disease ID | Disease Name | Definition | Mechanism | |
|---|---|---|---|---|
| No data available | ||||
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| S07 | Blockade of cytokine | Cytokine signalling | apremilast; roflumilast; filgotinib; tofacitinib; ABT494; ABT-874; ustekinumab; isankizumab; LY-2525623; AMG139; MEDI2079; guselkumab | Various T-cell subsets, their differentiation pathways and … | Details |