Drug ID:Drug105
Drug Name:Probiotic
CID:6713928
DrugBank ID:NULL
Modality:Small Molecule
Groups:NULL
US Approved:NULL
Other Approved:NULL
Identifier: NCT01479660, , NCT01765998, , NCT00161148, , NCT04223479
Molecular Formula:C17H19N3O4S
Molecular Weight:361.4 g/mol
Isomeric SMILES:CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N=C)C(=O)O)C
Synonyms:metampicillin; 6489-97-0; Micinovo; Viderpen; Ruticina; methylenampicillin; fedacilina; pravacilin; Metampicilina; Metampicilline
Phase 0: 0
Phase 1: 0
Phase 2: 0
Phase 3: 0
Phase 4: 0
Description:NULL

Molecular Structure

2D Molecular Structure

Knowledge Graph

dtIDCIDCompound NameGene IDGene NameSpeciesPubMed IDsAction
No data available

  • No data available

Phase Distribution
Phase Description
  • Phase 0: Exploratory trials to assess drug behavior in humans
  • Phase 1: Safety trials to determine safe dosage range
  • Phase 2: Efficacy trials to evaluate therapeutic effects
  • Phase 3: Large-scale trials to confirm efficacy and safety
  • Phase 4: Post-marketing surveillance for long-term safety and efficacy

Trial IDTitlePhaseStatusSponsorIndicationsInterventions
NCT07172139 Transcranial Magnetic Stimulation and Pharmacologic/Probiotic Interventions for Diarrhea-Predominant IBS NA NOT_YET_RECRUITING Rui Li IBS (Irritable Bowel Syndrome) COMBINATION_PRODUCT: Active rTMS + Pinaverium Bro… Details
NCT05663060 Evaluation Study of the Intestinal Microbiota and Quality of Life in Patients Suffering From IBS Treated With Bifidice NA COMPLETED Istituto Clinico Humanitas Irritable Bowel Syndrome DRUG: Probiotic Formula Details
NCT05652621 Efficacy of Probiotics in Patients With IBD NA RECRUITING The First Affiliated Hospital of Xinxiang Medical College Ulcerative Colitis|Irritable Bowel Syndrome DIETARY_SUPPLEMENT: probiotics Details
NCT05565612 Clinical Trial to Evaluate the Effect of a Probiotic Mixture on Signs and Symptoms of Irritable Bowel Syndrome NA COMPLETED Laboratorio Industrial de Herbodietetica Aplicada S.L IBS - Irritable Bowel Syndrome DIETARY_SUPPLEMENT: Normodigest Classic|DIETARY_S… Details
NCT05523427 Probiotics as Adjuvant Therapy in the Management of Irritable Bowel Syndrome NA COMPLETED University of Mosul Irritable Bowel Syndrome|Irritable Bowel Syndrome… DIETARY_SUPPLEMENT: Two probiotic strains (L. pla… Details
NCT05509725 Efficacy and Safety of a Probiotic Formulation in Adults With Irritable Bowel Syndrome With Diarrhea (IBS-D) PHASE4 UNKNOWN Lallemand Health Solutions IBS - Irritable Bowel Syndrome DRUG: Probiotic formulation|DRUG: Placebo Details
NCT05461833 FMT for Post-infectious IBS NA COMPLETED Bogomolets National Medical University Irritable Bowel Syndrome BIOLOGICAL: Fecal transplantation|DRUG: OTILONII … Details
NCT07149519 Impact of Dietary Guidance and Probiotics in the Treatment of Endometriosis and Irritable Bowel Syndrome in Women NA RECRUITING University of Sao Paulo Endometriosis|Bowels Irritable DIETARY_SUPPLEMENT: probiotics - Lactobacillus spp Details
NCT05366335 Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease PHASE4 UNKNOWN First Affiliated Hospital Xi'an Jiaotong University Functional Constipation|Irritable Bowel Syndrome|… DRUG: Live Combined Bifidobacterium and Lactobaci… Details
NCT05339243 Evaluating the Safety and Efficacy of the Probiotic Bifidobacterium Longum ES1 and the Post Biotic Heat-treated Bifidobacterium Longum ES1 (HT-ES1) on IBS Symptom Severity in Patients With Diarrhoea Predominant Irritable Bowel Syndrome NA COMPLETED Vedic Lifesciences Pvt. Ltd. Irritable Bowel Syndrome With Diarrhea OTHER: ES 1|OTHER: HT ES1|OTHER: Placebo Details
NCT07125625 Probiotic Mixture (L. Rhamnosus GG and L. Plantarum 299V) In Pediatric Irritable Bowel Syndrome NA NOT_YET_RECRUITING University of Bari Irritable Bowel Syndrome (IBS) DIETARY_SUPPLEMENT: Experimental arm: probiotic|D… Details
NCT05064930 The Efficacy of Single-strain Probiotics in Patients With Irritable Bowel Syndrome NA COMPLETED Nordic Biotic Sp. z o.o. Irritable Bowel Syndrome DIETARY_SUPPLEMENT: Probiotic Bifidobacterium lac… Details
NCT05013060 The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome NA COMPLETED Nordic Biotic Sp. z o.o. Irritable Bowel Syndrome DIETARY_SUPPLEMENT: Probiotics and microcapsulate… Details
NCT05001997 Effects of Lactose-free Dairy Products on Athletes With Irritable Bowel Syndrome NA UNKNOWN University of Central Lancashire Irritable Bowel Syndrome DIETARY_SUPPLEMENT: Lactose free probiotic yogurt Details
NCT04997057 A Multistrain Probiotic in Patients With Irritable Bowel Syndrome With Predominant Constipation NA COMPLETED CEN Biotech Irritable Bowel Syndrome With Constipation DIETARY_SUPPLEMENT: Probiotics mixture Details
NCT07094035 The Beneficial Effects on the Intestinal Function of a Food Supplement Based on an Extract of Green Tea and a Pool of Probiotics in Subjects With Irritable Bowel Syndrome With Predominance of Constipation NA RECRUITING Adamas Biotech S.r.l. IBS, Constipation Predominant DIETARY_SUPPLEMENT: food supplement based on a mi… Details
NCT04969679 Additive Effect of Probiotics (Mutaflor®) in Patients With Ulcerative Colitis on 5-ASA Treatment. PHASE4 COMPLETED Kangbuk Samsung Hospital Ulcerative Colitis DRUG: E. coli Nissle 1917 (Mutaflor®)|DRUG: Place… Details
NCT04898257 Effect of Lactibiane Tolerance® to Treat Leaky Gut in Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D)Patients NA COMPLETED Larena SAS IBS - Irritable Bowel Syndrome DIETARY_SUPPLEMENT: Multistrain probiotic Details
NCT04798417 Nutrition to Relieve IBS Constipation NA COMPLETED Wageningen University and Research Irritable Bowel Syndrome|Constipation DIETARY_SUPPLEMENT: Probiotic supplement|DIETARY_… Details
NCT04774042 Probiotic Supplementation in the Dysbiosis of Bowel Preparation NA UNKNOWN National Taiwan University Hospital Microbial Colonization|Irritable Bowel Syndrome|M… DIETARY_SUPPLEMENT: Infloran probiotic|DIETARY_SU… Details

Disease IDDisease NameDefinitionCategoryRelated DrugsMechanism
No data available

Strategy IDTherapeutic StrategySynonymsRelated DrugsMechanism
S11 Improveming Intestinal Microecology the intestinal microbiota antibiotics; probiotics; prebiotics; postbiotics; synbiotics; fecal microbiota transplantation (FMT) The imbalance between beneficial bacteria and harmful patho… Details

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