Drug ID:Drug169
Drug Name:SAR443122
CID:130298939
DrugBank ID:DB16492
Modality:Small Molecule
Groups:NULL
US Approved:NO
Other Approved:NO
Identifier: NCT05588843
Molecular Formula:C19H18N6O3
Molecular Weight:378.4 g/mol
Isomeric SMILES:CN1C(=O)[C@H](COC2=C1N=CC=C2)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4
Synonyms:Eclitasertib; 2125450-76-0; DNL758; Eclitasertib [INN]; Eclitasertib [USAN]; SAR443122; DNL-758; 975AT1P9J6; UNII-975AT1P9J6; SAR-443122
Phase 0: 0
Phase 1: 1
Phase 2: 2
Phase 3: 0
Phase 4: 0
Description:NULL

Molecular Structure

2D Molecular Structure

Knowledge Graph

dtIDCIDCompound NameGene IDGene NameSpeciesPubMed IDsAction
dt1247 130298939 Eclitasertib 8737 RIPK1 Homo sapiens (human) Inhibition
dt1248 130298939 Eclitasertib 2189 FANCG Homo sapiens (human) Inhibitor
dt1249 130298939 Eclitasertib 8737 RIPK1 Homo sapiens (human) Inhibitor

  • No data available

Phase Distribution
Phase Description
  • Phase 0: Exploratory trials to assess drug behavior in humans
  • Phase 1: Safety trials to determine safe dosage range
  • Phase 2: Efficacy trials to evaluate therapeutic effects
  • Phase 3: Large-scale trials to confirm efficacy and safety
  • Phase 4: Post-marketing surveillance for long-term safety and efficacy

Trial IDTitlePhaseStatusSponsorIndicationsInterventions
NCT05588843 Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis PHASE2 RECRUITING Sanofi Colitis Ulcerative DRUG: SAR443122|DRUG: Placebo Details

Disease IDDisease NameDefinitionCategoryRelated DrugsMechanism
No data available

Strategy IDTherapeutic StrategySynonymsRelated DrugsMechanism
No data available

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