Drug ID:Drug68
Drug Name:Propionyl-L-Carnitine
CID:188824
DrugBank ID:DB15980
Modality:Small Molecule
Groups:NULL
US Approved:NULL
Other Approved:NULL
Identifier: NCT01026857, , NCT01567956, , NCT01538251
Molecular Formula:C10H19NO4
Molecular Weight:217.26 g/mol
Isomeric SMILES:CCC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C
Synonyms:Propionyl-L-Carnitine; 20064-19-1; LEVOCARNITINE PROPIONATE; O-Propanoylcarnitine; O-propanoyl-carnitine; O-propanoyl-L-carnitine; L-Propionylcarnitine; 0HU2UI27HF; (3R)-3-propanoyloxy-4-(trimethylazaniumyl)butanoate; CHEBI:53210
Phase 0: 0
Phase 1: 0
Phase 2: 0
Phase 3: 0
Phase 4: 0
Description:NULL

Molecular Structure

2D Molecular Structure

Knowledge Graph

dtIDCIDCompound NameGene IDGene NameSpeciesPubMed IDsAction
No data available

  • No data available

Phase Distribution
Phase Description
  • Phase 0: Exploratory trials to assess drug behavior in humans
  • Phase 1: Safety trials to determine safe dosage range
  • Phase 2: Efficacy trials to evaluate therapeutic effects
  • Phase 3: Large-scale trials to confirm efficacy and safety
  • Phase 4: Post-marketing surveillance for long-term safety and efficacy

Trial IDTitlePhaseStatusSponsorIndicationsInterventions
NCT01567956 Propionyl-L-Carnitine Hydrochloride in Patients With Mild Ulcerative Colitis; Efficacy, Safety and Tolerability Study PHASE3 TERMINATED sigma-tau i.f.r. S.p.A. Ulcerative Colitis DRUG: Propionyl-L-Carnitine|DRUG: Placebo Details
NCT01538251 Efficacy, Safety and Tolerability of Propionyl-L-Carnitine Hydrochloride in Patients With Mild Ulcerative Colitis PHASE3 TERMINATED sigma-tau i.f.r. S.p.A. Ulcerative Colitis DRUG: Propionyl-L-Carnitine|DRUG: Placebo Details
EUCTR2009-013680-19-IT Phase II, Open, Monocenter Study to investigate the efficacy of Propionyl-L-carnitine (ST 261) Colon Release Tablets in Patients Affected by Inflammatory Bowel Disease (IBD) under Oral Stable Treatment - ND Not Available Not Recruiting POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IBD MedDRA version: 9.1_Level: PT_Classification… Pharmaceutical Form: Tablet INN or Proposed INN: … Details
NCT01026857 Propionyl-L-Carnitine in Ulcerative Colitis PHASE2 COMPLETED sigma-tau i.f.r. S.p.A. Ulcerative Colitis DRUG: Propionyl-L-Carnitine|DRUG: Propionyl-L-Car… Details

Disease IDDisease NameDefinitionCategoryRelated DrugsMechanism
No data available

Strategy IDTherapeutic StrategySynonymsRelated DrugsMechanism
No data available

Propionyl-L-carnitine hydrochloride for treatment of mild to moderate colonic i…

PMID: 23049215
Year: 2012
Relationship Type: Treatment Score: 6.1

AIM: To assess clinical and endoscopic response to propionyl-L-carnitine hydrochloride (PLC) in colonic inflammatory bowel disease. METHODS: Patients…

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