Drug ID:Drug84
Drug Name:Arm1
CID:3768902
DrugBank ID:NULL
Modality:Small Molecule
Groups:NULL
US Approved:NULL
Other Approved:NULL
Identifier: NCT06398808
Molecular Formula:C16H14N2S
Molecular Weight:266.4 g/mol
Isomeric SMILES:C1=CC=C(C=C1)CC2=CC=C(C=C2)C3=CSC(=N3)N
Synonyms:4-(4-benzylphenyl)-1,3-thiazol-2-amine; 68729-05-5; ARM1; 4-(4-Benzylphenyl)thiazol-2-amine; CHEMBL3883608; C16H14N2S; ARM-1; 1V6; 4l2l; 4BSA
Phase 0: 0
Phase 1: 0
Phase 2: 0
Phase 3: 0
Phase 4: 0
Description:NULL

Molecular Structure

2D Molecular Structure

Knowledge Graph

dtIDCIDCompound NameGene IDGene NameSpeciesPubMed IDsAction
No data available

  • No data available

Phase Distribution
Phase Description
  • Phase 0: Exploratory trials to assess drug behavior in humans
  • Phase 1: Safety trials to determine safe dosage range
  • Phase 2: Efficacy trials to evaluate therapeutic effects
  • Phase 3: Large-scale trials to confirm efficacy and safety
  • Phase 4: Post-marketing surveillance for long-term safety and efficacy

Trial IDTitlePhaseStatusSponsorIndicationsInterventions
NCT06398808 A Study to Evaluate the Efficacy and Safety of ZYIL1 Oral Capsules for the Treatment of Patients With Mild to Moderately Active Ulcerative Colitis Resistant or Intolerant to Oral Aminosalicylates PHASE2 COMPLETED Zydus Lifesciences Limited Ulcerative Colitis DRUG: Arm1|DRUG: Arm 2 Details

Disease IDDisease NameDefinitionCategoryRelated DrugsMechanism
No data available

Strategy IDTherapeutic StrategySynonymsRelated DrugsMechanism
No data available

Sarm1 Controls the MYD88-Mediated Inflammatory Responses in Inflammatory Bowel …

PMID: 38651786
Year: 2024
Relationship Type: Mechanism Score: 6.5

BACKGROUND: Sterile alpha and TIR motif-containing 1 (Sarm1) is known as a negative regulator of inflammatory responses. However, its role in inflamm…

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Sarm1-mediated neurodegeneration within the enteric nervous system protects aga…

PMID: 33871822
Year: 2021
Relationship Type: Association Score: 6.5

Axonal degeneration is one of the key features of neurodegenerative disorders. In the canonical view, axonal degeneration destructs neural connection…

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