A role for transcription factor NF-kappa B in intestinal inflammation
PMID: 10207726
Source: Int J Colorectal Dis
Publication date:
1999-04-20
Year:
1999
Abstract
Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.