Azathioprine
PMID: 30000109
Source: Drugs and Lactation Database (LactMed®)
Publication date:
2025-07-24
Year:
2006
Abstract
Studies in women with inflammatory bowel disease, systemic lupus erythematosus or transplantation taking doses of azathioprine up to 200 mg daily for immunosuppression have found either low or unmeasurable levels of the active metabolites in milk and infant serum. Some evidence indicates a lack of adverse effects on the health and development of infants exposed to azathioprine during breastfeeding up to 4.6 years of age, but long-term follow-up for effects such as carcinogenesis have not been performed. Numerous experts and professional guidelines have stated that the drug is a low risk to the nursing infant and acceptable to use during breastfeeding.[1-7]