Sulfasalazine
PMID: 31644099
Source: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
Publication date:
2025-07-24
Year:
2012
Abstract
Sulfasalazine is an antiinflammatory agent used extensively in chronic, long term therapy of inflammatory bowel disease. Sulfasalazine is structurally composed of a sulfonamide (sulfapyridine) and 5-aminosalacyclic acid (5-ASA) joined by an azo bond. Sulfasalazine is a rare, but well known cause of idiosyncratic liver injury.