We report the case of a 34-year-old female with Crohn's disease (CD), was treated with infliximab and ileocecal resection after failure to anti-TNF. She started adalimumab for postoperative recurrence for two years, with sustained clinical and endoscopic remission. She presents with a 1.5-year history of a persistent, asymptomatic, rubbery swelling on the left half of the lower lip.