Core Outcome Sets (COS) provide standardized outcomes for randomized controlled trials (RCTs), enhancing consistency and comparability in research. In inflammatory bowel disease (IBD), the CORE-IBD Collaborators developed the first COS for RCTs, while the European Crohn's and Colitis Organisation (ECCO) later introduced a COS for real-world data, addressing key domains such as disease activity, patient-reported outcomes, and healthcare utilization. Emerging imaging techniques are also shaping IBD research, likely influencing future COS development. Integrating COS into studies can improve evidence synthesis and foster a more standardized, patient-centered approach in IBD research and care.