BACKGROUND: Quantitative bowel motility in inflammatory bowel disease using magnetic resonance enterography (MRE) shows promise as a biomarker of disease activity against histopathological and biochemical markers of inflammation when used by experienced readers in a research setting. OBJECTIVE: The aim of this study was to test multi-reader agreement in quantified bowel motility by non-experienced readers. MATERIALS AND METHODS: A single-centre, retrospective search included all patients <18 years with paediatric inflammatory bowel disease and more than one MRE between 2012-2022. Cine images from the first two MREs were processed using quantified motility software. Two experienced readers provided a reference standard for response using a consensus sMaRIA (decrease of >/=2 points) and measured the change (Delta) in motility index. Two senior and three junior readers visually assessed response for each patient and recorded Delta motility index. Inter-reader agreement was assessed for each pair of readers as the Bland-Altman bias and limits of agreement for Delta motility index (arbitrary units, a.u.) and %agreement in the Deltadirection. RESULTS: Percentage agreement in the Deltadirection was fair to excellent. Junior reader agreement with experienced readers was 73-84%, and senior reader agreement with experienced readers was 67-85%. Bland-Altman plots of Delta motility index demonstrated no systematic bias and the junior-experienced readers' limits of agreement were acceptable. CONCLUSION: Quantified bowel motility in paediatric inflammatory bowel disease measured by readers of varied experience yields good agreement.