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Granzyme K drives a newly-intentified pathway of complement activation
Publication Year: 2024 Source: bioRxiv PMID: 38826230
No Abstract
A Paradigm For Calling Sequence In Families: The Long Life Family Study
Publication Year: 2024 Source: bioRxiv PMID: 38826248 DOI: 10.1101/2024.05.23.595584
Over Several years, we have developed a system for assuring the quality of whole genome sequence (WGS) data in the LLFS families. We have focused on providing data to identify germline genetic variants with the aim of releasing as many variants on as many individuals as possible. We aim to …
Outer Membrane Vesicles Derived from Adherent-Invasive Escherichia coli Induce Inflammatory Response and Alter the Gene Expression of Junction-Associated Proteins in Human Intestinal Epithelial Cells
Publication Year: 2024 Source: Can J Infect Dis Med Microbiol PMID: 38826676 DOI: 10.1155/2024/2701675
Adherent-invasive Escherichia coli (AIEC) pathobionts, which are characterized by their ability to adhere to and invade intestinal epithelial cells, are associated with the etiopathogenesis of inflammatory bowel diseases (IBDs). Outer membrane vesicles (OMVs) released by AIEC strains can facilitate the interaction of these bacteria with host cells through delivering bacterial …
Network Cluster Analysis of PPI and Phenotype Ontology for Type 1 Diabetes Mellitus
Publication Year: 2024 Source: Iran J Biotechnol PMID: 38827336
No Abstract
Pediatric inflammatory bowel disease: What's new and what has changed?
Publication Year: 2024 Source: Paediatr Child Health PMID: 38827368 DOI: 10.1093/pch/pxae013
The incidence and prevalence of inflammatory bowel disease (IBD) is on the rise in North America and worldwide, with young children being the fastest growing patient population. It is therefore essential for pediatricians and pediatric sub-specialists to be able to recognize signs and symptoms suspicious for a new diagnosis of …
INVITED COMMENTARY on Andersen S, et al. Developmental Windows of Environmental Vulnerability for Inflammatory Bowel Disease
Publication Year: 2024 Source: J Pediatr Clin Pract PMID: 38827481
No Abstract
Development and validation of a novel therapeutic drug monitoring-based nomogram for prediction of primary endoscopic response to anti-TNF therapy in active Crohn's disease
Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 38827646 DOI: 10.1177/17562848241256237
BACKGROUND: Anti-tumor necrosis factor (TNF) monoclonal antibodies, especially infliximab (IFX) and adalimumab (ADA), are considered the first-line treatment for active Crohn's disease (CD). However, the predictive role of therapeutic drug monitoring (TDM) of serum anti-TNF in monitoring the treatment of inflammatory bowel disease (IBD) remains controversial. OBJECTIVES: To explore the …
Time to grow up: readiness associated with improved clinical outcomes in pediatric inflammatory bowel disease patients undergoing transition
Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 38827647 DOI: 10.1177/17562848241241234
BACKGROUND: The transition from pediatric to adult healthcare in individuals with inflammatory bowel disease (IBD) poses significant challenges mainly due to the high burden of IBD during adolescence, a critical period of psychosocial development. So far, there are few longitudinal data linking transition readiness to long-term disease outcomes. OBJECTIVE: We …
Squamous cell carcinoma and Crohn's disease: a sometimes-challenging diagnosis
Publication Year: 2024 Source: Future Sci OA PMID: 38827804
No Abstract
Repurposing disulfiram with CuET nanocrystals: Enhancing anti-pyroptotic effect through NLRP3 inflammasome inhibition for treating inflammatory bowel diseases
Publication Year: 2024 Source: Acta Pharm Sin B PMID: 38828135
No Abstract
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