Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Bifidobacterium bifidum Ameliorates DSS-Induced Colitis in Mice by Regulating Microbial Metabolome and Targeting Gut Microbiota
Publication Year: 2024 Source: J Agric Food Chem PMID: 38838169 DOI: 10.1021/acs.jafc.4c00365
Inflammatory bowel disease (IBD) is a recurrent inflammatory condition affecting the gastrointestinal tract, and its clinical treatment remains suboptimal. Probiotics have shown effectiveness in alleviating dextran sulfate sodium salt (DSS)-induced colitis, exhibiting strain-specific anti-inflammatory properties. In this study, we compared the therapeutic effects of five strains of Bifidobacterium bifidum isolated …
Clinical features and lymphocyte immunophenotyping analysis in primary immunodeficiency patients with non-transplant lymphoproliferative disorders
Publication Year: 2024 Source: Clin Immunol PMID: 38838929 DOI: 10.1016/j.clim.2024.110269
Lymphoproliferative disorders (LPD) comprise a heterogeneous group and are originally classified into the "Disease of immune dysregulation" category. Of 96 Taiwanese patients during 2003-2022, 31 (median 66, range 0.03-675 months) developed LPD, mainly including palpable lymphadenopathy (in 10 patients), intestinal lymphadenopathy associated with refractory inflammatory bowel disease (IBD in 8) …
Does Improving Depression Symptoms in Young Adults With Inflammatory Bowel Disease Alter Their Microbiome?
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38839073 DOI: 10.1093/ibd/izae121
BACKGROUND: Patients with inflammatory bowel diseases (IBDs) are more likely to have depression and anxiety symptoms compared with healthy individuals and those with other chronic illnesses. Previous studies have shown a link between the microbiome composition and depression symptoms; however, many antidepressant medications have antibacterial activity confounding cross-sectional studies of …
Protective function of sclerosing cholangitis on IBD
Publication Year: 2024 Source: Gut PMID: 38839272 DOI: 10.1136/gutjnl-2023-330856
OBJECTIVE: There is a strong clinical association between IBD and primary sclerosing cholangitis (PSC), a chronic disease of the liver characterised by biliary inflammation that leads to strictures and fibrosis. Approximately 60%-80% of people with PSC will also develop IBD (PSC-IBD). One hypothesis explaining this association would be that PSC …
Persistence, effectiveness and safety of ustekinumab and vedolizumab therapy for complex perianal fistula in Crohn's disease: The HEAL study from GETECCU
Publication Year: 2024 Source: Dig Liver Dis PMID: 38839456
No Abstract
The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease
Publication Year: 2024 Source: Nat Commun PMID: 38839750 DOI: 10.1038/s41467-024-49049-8
The metal ion transporter SLC39A8 is associated with physiological traits and diseases, including blood manganese (Mn) levels and inflammatory bowel diseases (IBD). The mechanisms by which SLC39A8 controls Mn homeostasis and epithelial integrity remain elusive. Here, we generate Slc39a8 intestinal epithelial cell-specific-knockout (Slc39a8-IEC KO) mice, which display markedly decreased Mn …
Azathioprine promotes intestinal epithelial cell differentiation into Paneth cells and alleviates ileal Crohn's disease severity
Publication Year: 2024 Source: Sci Rep PMID: 38839896
No Abstract
Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria
Publication Year: 2024 Source: Nat Biomed Eng PMID: 38839928
No Abstract
Profiling phagosome proteins identifies PD-L1 as a fungal-binding receptor
Publication Year: 2024 Source: Nature PMID: 38839956
No Abstract
A disease-associated gene desert directs macrophage inflammation through ETS2
Publication Year: 2024 Source: Nature PMID: 38839969
No Abstract
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide