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[Extra-intestinal manifestations associated with Crohn's disease]
Publication Year: 2024 Source: Ned Tijdschr Geneeskd PMID: 38780190
No Abstract
Anti-Inflammatory Potential of Beclometasone-Loaded Filomicelles on Activated Human Monocytes
Publication Year: 2024 Source: Macromol Biosci PMID: 38780274 DOI: 10.1002/mabi.202400179
Polymeric micelles with a hydrophobic core represent versatile nanostructures for encapsulation and delivery of water-insoluble drugs. Here, water-insoluble beclometasone dipropionate (BDP) which is a potent anti-inflammatory therapeutic agent but limited to topical applications so far, is encapsulated. Therefore, this work used an amphiphilic block copolymer self-assembling into flexible polymeric filomicelles, …
Effectiveness and Safety of Ustekinumab in Pediatric Ulcerative Colitis: A Multi-center Retrospective Study from the Pediatric IBD Porto Group of ESPGHAN
Publication Year: 2024 Source: Paediatr Drugs PMID: 38780740 DOI: 10.1007/s40272-024-00631-z
BACKGROUND AND OBJECTIVES: Current data on ustekinumab therapy in children with ulcerative colitis (UC) or unclassified inflammatory bowel disease (IBDU) are limited. We aimed to evaluate the effectiveness and safety of ustekinumab in pediatric UC and IBDU. METHODS: This multicenter retrospective study included 16 centers affiliated with the IBD Interest …
Sleep patterns, genetic susceptibility, and digestive diseases: a large-scale longitudinal cohort study
Publication Year: 2024 Source: Int J Surg PMID: 38781035
No Abstract
Cryo-EM structure of I domain-containing integrin αEβ7
Publication Year: 2024 Source: Biochem Biophys Res Commun PMID: 38781659 DOI: 10.1016/j.bbrc.2024.150121
The integrin family is a transmembrane receptor that plays critical roles in the cell-cell and cell-extracellular matrix adhesion, signal transduction such as cell cycle regulation, organization of the intracellular cytoskeleton, and immune responses. Consequently, dysfunction of integrins is associated with a wide range of human diseases, including cancer and immune …
Sex-Related Differences in the Phenotype and Course of Inflammatory Bowel Disease: SEXEII Study of ENEIDA
Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 38782172 DOI: 10.1016/j.cgh.2024.05.013
BACKGROUND & AIMS: The impact of patient sex on the presentation of inflammatory bowel disease (IBD) has been poorly evaluated. Our aims were to assess potential disparities in IBD phenotype and progression between sexes. METHODS: We performed an observational multicenter study that included patients with Crohn's disease (CD) or ulcerative …
Deferasirox film-coated tablet-associated ulcerative colitis: An emerging pattern in thalassemia patients?
Publication Year: 2024 Source: Br J Haematol PMID: 38782586
No Abstract
Spatial features of skip lesions in Crohn's disease
Publication Year: 2024 Source: Trends Immunol PMID: 38782626
No Abstract
Calcium deficiency is associated with malnutrition risk in patients with inflammatory bowel disease
Publication Year: 2024 Source: Postgrad Med PMID: 38782760 DOI: 10.1080/00325481.2024.2359895
BACKGROUND AND AIM: Patients with inflammatory bowel disease (IBD) often have the condition of malnutrition, which can be presented as sarcopenia, micronutrient deficiencies, etc. Trace elements (magnesium, calcium, iron, copper, zinc, plumbum and manganese) belonging to micronutrients, are greatly vital for the assessment of nutritional status in humans. Trace element …
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