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Helicobacter Pylori infection in children with inflammatory bowel disease: a prospective multicenter study
Publication Year: 2024 Source: BMC Pediatr PMID: 38951792 DOI: 10.1186/s12887-024-04902-z
BACKGROUND: The relationship between Helicobacter-pylori(Hp)infection and inflammatory-bowel-disease(IBD) in pediatric-patients remains controversial. We aimed to assess the Hp-infection occurrence in newly-diagnosed pediatric-patients with IBD compared to no-IBD patients. Additionally, we aimed to examine differences in clinical-activity-index(CAI) and endoscopic-severity-score(ESS)between IBD-patients with and without Hp-infection, at baseline and at 1-year-follow-up(FU), after eradication-therapy(ET). METHODS: …
CViewer: a Java-based statistical framework for integration of shotgun metagenomics with other omics datasets
Publication Year: 2024 Source: Microbiome PMID: 38951915
No Abstract
Duration of Postvaccination Neutralizing Antibodies to SARS-CoV-2 and Medication Effects: Results from the Safety and Immunogenicity of COVID-19 Vaccination in Systemic Immune-Mediated Inflammatory Diseases Cohort Study
Publication Year: 2024 Source: ACR Open Rheumatol PMID: 38952080
No Abstract
[Knock-down of long noncoding RNA H19 (lncRNA H19) promotes human colorectal cell autophagy and inhibits cell apoptosis induced by lipopolysaccharide]
Publication Year: 2024 Source: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi PMID: 38952094
No Abstract
Association of diet and outdoor time with inflammatory bowel disease: a multicenter case-control study using propensity matching analysis in China
Publication Year: 2024 Source: Front Public Health PMID: 38952728 DOI: 10.3389/fpubh.2024.1368401
OBJECTIVE: To investigate the association between dietary and some other environmental factors and the risk of inflammatory bowel diseases (IBD) in Chinese population. MATERIALS AND METHODS: A multicenter case-control study was conducted involving 11 hospitals across China. A total of 1,230 subjects were enrolled consecutively, and diet and environmental factor …
Risk of Hematologic Malignancies in Patients with Inflammatory Bowel Disease: A Meta-Analysis of Cohort Studies
Publication Year: 2024 Source: Gut Liver PMID: 38953119 DOI: 10.5009/gnl240119
BACKGROUND/AIMS: Inflammatory bowel disease (IBD) may contribute to the development of hematologic malignancies. In this study, the potential relationship between IBD and hematologic malignancies was investigated. METHODS: We searched the PubMed, Web of Science, Embase, and Cochrane Library databases for all cohort studies comparing the incidence of hematologic malignancies in …
Ileal Paneth Cell Phenotype is a Cellular Biomarker for Pouch Complications in Ulcerative Colitis
Publication Year: 2024 Source: J Crohns Colitis PMID: 38953127 DOI: 10.1093/ecco-jcc/jjae105
BACKGROUND & AIMS: Biomarkers that integrate genetic and environmental factors and predict outcome in complex immune diseases such as inflammatory bowel disease (IBD; including Crohn's disease [CD] and ulcerative colitis [UC]) are needed. We showed that morphologic patterns of ileal Paneth cells (Paneth cell phenotype [PCP]; a surrogate for PC …
[Correlations Between the Expression of MicroRNA-155 and Suppressor of Cytokine Signaling 1 in Colonic Mucosal Tissue and Disease Severity in Patients With Ulcerative Colitis]
Publication Year: 2024 Source: Zhongguo Yi Xue Ke Xue Yuan Xue Bao PMID: 38953257
No Abstract
Allium tuberosum-derived nanovesicles with anti-inflammatory properties prevent DSS-induced colitis and modify the gut microbiome
Publication Year: 2024 Source: Food Funct PMID: 38953279 DOI: 10.1039/d4fo01366b
Edible plant-derived nanovesicles (ePDNs) have shown potential as a non-pharmacological option for inflammatory bowel disease (IBD) by maintaining gut health and showing anti-inflammatory effects. However, the effects of Allium tuberosum-derived nanovesicles (ADNs) on colitis have not been studied to date. Here, we extracted exosome-like nanovesicles from Allium tuberosum and investigated …
Development and investigation of a non-invasive disease severity index for inflammatory bowel disease
Publication Year: 2024 Source: J Crohns Colitis PMID: 38953471 DOI: 10.1093/ecco-jcc/jjae106
INTRODUCTION: The disease severity index (DSI) encapsulates the inflammatory bowel disease (IBD) burden but requires endoscopic investigations. This study developed a non-invasive DSI using faecal calprotectin (DSI-fCal) and faecal myeloperoxidase (DSI-fMPO) instead of colonoscopy. METHODS: Adults with IBD were recruited prospectively. Baseline biomarker concentrations were used to develop DSI-fCal and …
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