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Methotrexate accumulation in target intestinal mucosa and white blood cells differs from non-target red blood cells of patients with Crohn's disease
Publication Year: 2024 Source: Basic Clin Pharmacol Toxicol PMID: 38973551
No Abstract
pH-Sensitive Hydrogels Fabricated with Hyaluronic Acid as a Polymer for Site-Specific Delivery of Mesalamine
Publication Year: 2024 Source: ACS Omega PMID: 38973903
No Abstract
Assessing the correlation between fecal calprotectin, blood markers and disease activity in pediatric inflammatory bowel disease
Publication Year: 2024 Source: Ann Gastroenterol PMID: 38974077 DOI: 10.20524/aog.2024.0892
BACKGROUND: Crohn's disease (CD) and ulcerative colitis (UC) are the 2 main types of inflammatory bowel disease (IBD), a chronic inflammatory condition of the gastrointestinal tract. Management of IBD necessitates frequent clinical monitoring, including blood tests and occasionally endoscopy. Fecal calprotectin (FC) is a non-invasive measurement of luminal inflammatory activity, …
Clinical outcomes of flavonoids for immunomodulation in inflammatory bowel disease: a narrative review
Publication Year: 2024 Source: Ann Gastroenterol PMID: 38974082
No Abstract
The national burden of inflammatory bowel disease in the United States from 1990-2019: results from the Global Burden of Disease study database
Publication Year: 2024 Source: Ann Gastroenterol PMID: 38974084 DOI: 10.20524/aog.2024.0894
BACKGROUND: Inflammatory bowel disease (IBD) epidemiology has changed rapidly in recent years. We aimed to provide a systematic report of the burden of IBD at a state level in the United States (US), and to study the age- and sex-specific trends of incidence, prevalence and mortality rates for the past …
Current Research on the Role of Isomaltooligosaccharides in Gastrointestinal Health and Metabolic Diseases
Publication Year: 2024 Source: Prev Nutr Food Sci PMID: 38974594 DOI: 10.3746/pnf.2024.29.2.93
The intestinal epithelium plays an important role in maintaining the intestinal barrier and facilitating nutrient absorption. It also serves as a critical physical barrier against the infiltration of foreign substances from the intestinal lumen into the circulation. Intestinal barrier dysfunction has been implicated in the development of several diseases. Isomaltooligosaccharides …
Nonendemic rhinoscleroma: An unusual manifestation of the trachea
Publication Year: 2024 Source: Laryngoscope Investig Otolaryngol PMID: 38974602
No Abstract
Does Timing of Ileal Pouch-Anal Anastomosis Matter in Patients With Primary Sclerosing Cholangitis and Orthotopic Liver Transplantation? A Systematic Review and Meta-analysis
Publication Year: 2024 Source: Crohns Colitis 360 PMID: 38974606 DOI: 10.1093/crocol/otae036
INTRODUCTION: Pouchitis is the most common complication in patients with ileal pouch-anal anastomosis (IPAA), which can develop in up to 66% of patients. There is limited data on the effect of orthoptic liver transplantation (OLT) on the risk of developing pouchitis. We aimed to objectively assess whether OLT itself significantly …
Real-life treatment persistence and treatment outcomes of Finnish patients with inflammatory bowel disease receiving vedolizumab as first-line biological treatment
Publication Year: 2024 Source: Heliyon PMID: 38975101
No Abstract
Advancements in Targeted Therapies for the Management of Crohn's Disease: A Comprehensive Review
Publication Year: 2024 Source: Cureus PMID: 38975385 DOI: 10.7759/cureus.61751
Crohn's disease (CD) is a complex clinical condition characterized by persistent gastrointestinal inflammation that leads to episodes of flare-ups and subsequent healing. The treatment options for this disease are heterogeneous as its impact on different patients is also different. This study aims to evaluate the effectiveness of recently approved drugs …
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