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Induction and maintenance of mucosal healing in Crohn's disease with ustekinumab in clinical practice across all care levels in Germany (MUCUS)

Publication Year: 2024 Source: Sci Rep PMID: 39227642

No Abstract

Berberine and magnolol exert cooperative effects on ulcerative colitis in mice by self-assembling into carrier-free nanostructures

Publication Year: 2024 Source: J Nanobiotechnology PMID: 39227962

No Abstract

Tissue engineering and regenerative medicine approaches in colorectal surgery

Publication Year: 2024 Source: Ann Coloproctol PMID: 39228197

No Abstract

Feasibility and acceptability of remote administration of the cold pressor test

Publication Year: 2024 Source: Front Pain Res (Lausanne) PMID: 39228685

No Abstract

Safety and effectiveness of additional triamcinolone acetonide with endoscopic radial incision and cutting for benign stenosis of the lower gastrointestinal tract: A pilot study

Publication Year: 2024 Source: DEN Open PMID: 39228860

No Abstract

Depression influences fatigue in inflammatory bowel disease amongst other factors: a structural modelling approach

Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 39228998 DOI: 10.1177/17562848241271987

OBJECTIVES: Fatigue is common in people with inflammatory bowel disease (IBD) and is associated with IBD activity, sleep disturbance, anxiety and depression. The relative contribution of these factors to fatigue is unclear. This study aimed to investigate the relationship between fatigue and these factors through a novel approach using structural …

Peripheral Blood Immune Cells from Individuals with Parkinson's Disease or Inflammatory Bowel Disease Share Deficits in Iron Storage and Transport that are Modulated by Non-Steroidal Anti-Inflammatory Drugs

Publication Year: 2024 Source: bioRxiv PMID: 39229100 DOI: 10.1101/2024.08.19.608634

Parkinson's Disease (PD) is a multisystem disorder in which dysregulated neuroimmune crosstalk and inflammatory relay via the gut-blood-brain axis have been implicated in PD pathogenesis. Although alterations in circulating inflammatory cytokines and reactive oxygen species (ROS) have been associated with PD, no biomarkers have been identified that predict clinical progression …

Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis

Publication Year: 2024 Source: bioRxiv PMID: 39229116 DOI: 10.1101/2024.08.22.609271

BACKGROUND & AIMS: Ulcerative colitis (UC) is associated with epithelial metabolic derangements which exacerbate gut inflammation. Patient-derived organoids recapitulate complexities of the parent tissue in health and disease; however, whether colon organoids (colonoids) model metabolic impairments in the pediatric UC epithelium is unclear. This study determined the functional metabolic differences …

Lymphocyte subsets for predicting inflammatory bowel disease progression and treatment response: a systematic review

Publication Year: 2024 Source: Front Immunol PMID: 39229260 DOI: 10.3389/fimmu.2024.1403420

BACKGROUND: Lymphocytes play a key role in the pathogenesis of inflammatory bowel disease (IBD) and are widely explored as promising prognostic indicators. We aimed to outline the existing evidences on the capability of lymphocyte subpopulations to predict disease progression and treatment response in patients with IBD. METHODS: The protocol for …

Regulation of Bacteroides acidifaciens by the aryl hydrocarbon receptor in IL-22-producing immune cells has sex-dependent consequential impact on colitis

Publication Year: 2024 Source: Front Immunol PMID: 39229279 DOI: 10.3389/fimmu.2024.1444045

INTRODUCTION: Colitis is an inflammatory bowel disease (IBD) characterized by immune cell dysregulation and alterations in the gut microbiome. In our previous report, we showed a natural product in cruciferous vegetables and ligand of the aryl hydrocarbon receptor (AhR), indole-3-carbinol (I3C), was able to reduce colitis-induced disease severity and microbial …

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