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Comment on "Targeted surgery combined with postoperative medical therapy for residual disease for severe and multifocal Crohn disease"

Publication Year: 2024 Source: Surgery PMID: 39237434

No Abstract

Orally biomimetic metal-phenolic nanozyme with quadruple safeguards for intestinal homeostasis to ameliorate ulcerative colitis

Publication Year: 2024 Source: J Nanobiotechnology PMID: 39238009

No Abstract

Duodenal and colonic mucosal S100A8/A9 (calprotectin) expression is increased and correlates with the severity of select histologic lesions in dogs with chronic inflammatory enteropathy

Publication Year: 2024 Source: BMC Vet Res PMID: 39238011

No Abstract

The landscape of miRNA-mRNA regulatory network and cellular sources in inflammatory bowel diseases: insights from text mining and single cell RNA sequencing analysis

Publication Year: 2024 Source: Front Immunol PMID: 39238649 DOI: 10.3389/fimmu.2024.1454532

BACKGROUND: Inflammatory Bowel Diseases (IBDs), encompassing Ulcerative Colitis (UC) and Crohn's Disease (CD), are chronic, recurrent inflammatory conditions of the gastrointestinal tract. The microRNA (miRNA) -mRNA regulatory network is pivotal in the initiation and progression of IBDs. Although individual studies provide valuable insights into miRNA mechanisms in IBDs, they often …

Micronutrient deficiencies in older patients with inflammatory bowel disease are not associated with worse adverse clinical outcome rates

Publication Year: 2024 Source: Ann Gastroenterol PMID: 39238798 DOI: 10.20524/aog.2024.0900

BACKGROUND: Micronutrient deficiencies (MNDs) and age have been previously separately associated with adverse clinical outcomes in patients with inflammatory bowel disease (IBD). However, previous clinical outcomes in older patients with MNDs have been poorly described. We examined the age-related rates of adverse clinical outcomes in patients with 1 or more …

Inflammatory bowel disease burden in the Middle East and North Africa Region: a comprehensive analysis of incidence, prevalence, and mortality from 1990-2019

Publication Year: 2024 Source: Ann Gastroenterol PMID: 39238799 DOI: 10.20524/aog.2024.0909

BACKGROUND: The epidemiology of inflammatory bowel disease (IBD) has changed rapidly in recent years. Objective data concerning the IBD burden in the Middle East and North Africa (MENA) region is limited. We aimed to provide a systematic report on the IBD burden in the MENA region. Additionally, we aimed to …

Effectiveness of autologous emulsified stromal vascular fraction tissue injection for the treatment of complex perianal fistulas in inflammatory bowel diseases patients: a pilot study

Publication Year: 2024 Source: Therap Adv Gastroenterol PMID: 39239070 DOI: 10.1177/17562848241263014

Complex fistulizing perianal disease is a disabling manifestation of inflammatory bowel disease (IBD), seriously compromising patients 'quality of life'. The success rate of available treatments is quite low, and nearly half of the patients will develop chronically active fistulas or experience fistula recurrence. Mesenchymal stem cell therapy has shown interesting …

Dorsal root ganglion stimulation provides significant functional improvement from acute debilitating Crohn's disease: A novel use

Publication Year: 2024 Source: Interv Pain Med PMID: 39239493 DOI: 10.1016/j.inpm.2024.100389

Crohn's disease is a chronic inflammatory bowel condition causing symptoms, notably pain, due to ongoing intestinal inflammation or complications like abscesses, strictures, and fistulas, which are common in IBD patients. Abdominal pain affects up to 60 % of IBD patients, irrespective of disease severity, prompting medical attention. Various medications like …

Rafoxanide negatively modulates STAT3 and NF-κB activity and inflammation-associated colon tumorigenesis

Publication Year: 2024 Source: Cancer Sci PMID: 39239848

No Abstract

Concomitant management of alopecia universalis and ulcerative colitis with upadacitinib

Publication Year: 2024 Source: Intern Med J PMID: 39239955

No Abstract

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