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The Clinical Interpretation of Cluster Trials

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39495043

Cluster-randomized trials randomize entire groups of participants, instead of individual participants, to different treatment arms. For certain interventions (eg, institutional policies, processes of care, treatment algorithms), these designs protect against contamination between study arms. However, cluster trials are logistically complex to implement and have unique vulnerabilities that must be evaluated …

Editorial: Disentangling Early-Life Antibiotics and Infections as Risk Factors for the Development of Childhood IBD

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39495055 DOI: 10.1111/apt.18374

No Abstract

Symptomatic and Sonographic Improvement of Immune Checkpoint Inhibitor Enterocolitis With Risankizumab

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39495057

No Abstract

Functional analysis of antigen presentation by enteric glial cells during intestinal inflammation

Publication Year: 2025 Source: Glia PMID: 39495092

No Abstract

Assessment of Treatment Response in Known Crohn's Disease-A Prospective Blinded Study Comparing the Diagnostic Accuracy of Intestinal Ultrasound, Magnetic Resonance Enterocolonography, Panenteric Capsule Endoscopy, and Fecal Calprotectin

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39495122

BACKGROUND: Minimally invasive modalities may replace ileocolonoscopy (IC) in the follow-up of Crohn's disease (CD). The aim of this study was to evaluate intestinal ultrasound (IUS), magnetic resonance enterocolonography (MREC), panenteric capsule endoscopy (PCE), and fecal calprotectin (FC) for determining response to medical treatment in patients with ileocolonic CD. METHODS: …

Contemporary and prospective use of azathioprine (AZA) in viral, rheumatic, and dermatological disorders: a review of pharmacogenomic and nanotechnology applications

Publication Year: 2025 Source: Naunyn Schmiedebergs Arch Pharmacol PMID: 39495265

No Abstract

Characterization of Inflammatory Bowel Disease Heterogeneity Using Serum Proteomics: A Multicenter Study

Publication Year: 2025 Source: J Crohns Colitis PMID: 39495605 DOI: 10.1093/ecco-jcc/jjae169

BACKGROUND: Recent genetic and transcriptomic data highlight the need for improved molecular characterization of inflammatory bowel disease (IBD). Proteomics may advance the delineation of IBD phenotypes since it accounts for post-transcriptional modifications. AIMS: We aimed to assess the IBD spectrum based on inflammatory serum proteins and identify discriminative patterns of …

Endoplasmic Reticular Stress and Pathogenesis of Experimental Colitis: Mechanism of Action of 5-Amino Salicylic Acid

Publication Year: 2025 Source: Med Princ Pract PMID: 39496247

No Abstract

Long-term clinical and endoscopic outcomes of ustekinumab in pediatric Crohn's disease with anti-tumor necrosis factor failure

Publication Year: 2025 Source: J Gastroenterol Hepatol PMID: 39496363

No Abstract

Artificial intelligence-aided colonoscopic differential diagnosis between Crohn's disease and gastrointestinal tuberculosis

Publication Year: 2025 Source: J Gastroenterol Hepatol PMID: 39496468

No Abstract

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