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Risk Factors for Recurrence of Crohn's Disease After Ileocecal Resection and Management Strategies
Publication Year: 2025 Source: J Pediatr Surg PMID: 39358079
No Abstract
Darvadstrocel for complex perianal fistulas in Crohn's disease: A systematic review and meta-analysis
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39360706
No Abstract
Diagnosis and Management of Inflammatory Bowel Disease-Associated Spondyloarthritis
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39360937 DOI: 10.14309/ajg.0000000000003092
Inflammatory bowel disease (IBD)-associated spondyloarthritis (SpA) is common but remains poorly understood. In this review article, we aimed to provide guidance regarding the diagnosis and management of this condition. For diagnosis of IBD-associated peripheral SpA (IBD-pSpA), we recommend collaboration with rheumatology for incorporation of clinical symptoms, physical examination findings, joint …
Association between depression and anxiety with the risk and flare of inflammatory bowel disease: a systematic review and meta-analysis
Publication Year: 2025 Source: Intern Emerg Med PMID: 39361221 DOI: 10.1007/s11739-024-03764-8
Inflammatory bowel disease (IBD) is a chronic condition characterized by inflammation in the gastrointestinal tract. Previous studies have suggested a potential association between mental disorders, such as depression and anxiety, and the risk and flare of IBD. However, the findings have been inconsistent. This study aimed to conduct a systematic …
Crohn's Disease and Ulcerative Colitis Share 2 Molecular Subtypes With Different Mechanisms and Drug Responses
Publication Year: 2025 Source: J Crohns Colitis PMID: 39361323
BACKGROUND AND AIMS: Several therapies have been approved to treat Crohn's disease (CD) and ulcerative colitis (UC), indicating that both diseases may share the same molecular subtypes. The aim of this study is to identify shared patient subtypes with common molecular drivers of disease. METHODS: Five public datasets with 406 …
Use of FISH-FLOW as a Method for the Identification and Quantification of Bacterial Populations
Publication Year: 2025 Source: Mol Nutr Food Res PMID: 39363651 DOI: 10.1002/mnfr.202400494
The gastrointestinal tract (GIT) harbors the largest group of microbiotas among the microbial communities of the human host. The resident organisms typical of a healthy gut are well adapted to the gastrointestinal environment while alteration of these populations can trigger disorders that may affect the health and well-being of the …
Gallstone Disease Is Associated With an Increased Risk of Inflammatory Bowel Disease: Results From 3 Prospective Cohort Studies
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39364876 DOI: 10.14309/ajg.0000000000003111
INTRODUCTION: Gallstone diseases affect intestinal inflammation, bile flow, and gut microbiota, which in turn may increase the risk of inflammatory bowel disease (IBD). However, epidemiological studies exploring the associations between gallstone diseases and subsequent IBD risk have been limited. METHODS: This is a combined analysis of 3 prospective cohort studies …
The Circulating Methylome in Childhood-Onset Inflammatory Bowel Disease
Publication Year: 2025 Source: J Crohns Colitis PMID: 39365013 DOI: 10.1093/ecco-jcc/jjae157
BACKGROUND: The genetic contribution to inflammatory bowel disease (IBD), encompassing both Crohn's disease (CD) and ulcerative colitis (UC), accounts for around 20% of disease variance, highlighting the need to characterize environmental and epigenetic influences. Recently, considerable progress has been made in characterizing the adult methylome in epigenome-wide association studies. METHODS: …
Exploring the role of genetics, gut microbiota and blood metabolites in IBD
Publication Year: 2025 Source: Gut PMID: 39366724 DOI: 10.1136/gutjnl-2024-333611
No Abstract
Letter: Differences in Disease Characteristics and Treatment Exposures Between Paediatric and Adult-Onset IBD
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39367641 DOI: 10.1111/apt.18313
No Abstract
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