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Uncovering the pharmacological mechanisms of Patchouli essential oil for treating ulcerative colitis
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39182705
No Abstract
Comparative Efficacy of Biologics and Small Molecule in Ulcerative Colitis: A Systematic Review and Network Meta-analysis
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39182898
No Abstract
Prevalence of Sexual Dysfunction in Inflammatory Bowel Disease: Systematic Review and Meta-analysis
Publication Year: 2025 Source: J Crohns Colitis PMID: 39185800 DOI: 10.1093/ecco-jcc/jjae133
BACKGROUND AND AIMS: Patients with inflammatory bowel disease (IBD) may experience symptoms of sexual dysfunction (SD). However, the magnitude of this problem remains uncertain. Therefore, we performed a systematic review and meta-analysis to assess the prevalence of SD in adult patients with IBD. METHODS: MEDLINE, EMBASE, and EMBASE Classic (from …
Upadacitinib for Acute Severe Ulcerative Colitis: A Systematic Review
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39186564
Acute severe ulcerative colitis (ASUC) remains a clinical challenge associated with considerable morbidity, including colectomy. Upadacitinib (UPA), a selective Janus kinase (JAK)-1 inhibitor, is approved for moderate-to-severe ulcerative colitis in patients intolerant or not responding to tumor necrosis factor-alpha inhibitors. It has also increasingly been used off-label for ASUC. We …
Deer oil improves ulcerative colitis induced by DSS in mice by regulating the intestinal microbiota and SCFAs metabolism and modulating NF-κB and Nrf2 signaling pathways
Publication Year: 2025 Source: J Sci Food Agric PMID: 39189446
No Abstract
A Study of Patient Concerns in the Modern Therapeutic Era of Inflammatory Bowel Disease
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39190809 DOI: 10.1093/ibd/izae197
BACKGROUND: Patient concerns and preferences are important in the management of inflammatory bowel disease (IBD: Crohn's disease [CD], ulcerative colitis). In the absence of contemporary data, we aimed to determine patient concerns and preferences and establish if there are demographic or disease-related differences. METHODS: We surveyed patients with IBD at …
Psychometric Evaluation of the Bengali Short Form 12 Version 2 Health Survey in Patients With Inflammatory Bowel Disease
Publication Year: 2025 Source: Value Health Reg Issues PMID: 39190975 DOI: 10.1016/j.vhri.2024.101036
OBJECTIVES: Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, significantly affects health-related quality of life (HRQOL). Despite the widespread use of the Short Form 12 version 2 (SF-12v2) questionnaire to assess HRQOL, its validity and reliability in Bengali IBD populations remain unclear. Our study aimed to evaluate the …
Psychological Distress Is Associated With Inflammatory Bowel Disease Manifestation and Mucosal Inflammation
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39191508 DOI: 10.1093/ibd/izae180
BACKGROUND: Stress is a potentially significant risk factor for the occurrence and progression of inflammatory bowel disease (IBD). METHODS: The study analyzed the level of stress, anxiety, and depression in patients with Crohn's disease (CD; n = 50) and ulcerative colitis (UC; n = 54) in comparison with non-IBD controls …
The Potential of Molecular Remission: Tissue Neutrophil Elastase Is Better Than Histological Activity for Predicting Long-Term Relapse in Patients With Ulcerative Colitis in Endoscopic Remission
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39191527
BACKGROUND: Growing interest exists in deep remission, beyond clinical and endoscopic remission, to enhance long-term prognosis in patients with ulcerative colitis (UC). Our study aimed to evaluate the risk of relapse according to tissue expression levels of calprotectin and neutrophil elastase (NE) in patients with quiescent UC. METHODS: Rectal biopsies …
Meta-analysis of the Therapeutic Impact of Cannabinoids in Inflammatory Bowel Disease
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39197096
BACKGROUND: With the increasing legalization of medical and recreational cannabis, patients and providers have growing interest in the role of cannabinoids in treating inflammatory bowel disease. Prior meta-analysis has shown inconclusive evidence for efficacy of cannabinoids. We sought to produce an up-to-date meta-analysis that pools new data to evaluate the …
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