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The Cost of Inflammatory Bowel Disease Care: How to Make it Sustainable
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39151644 DOI: 10.1016/j.cgh.2024.06.049
The rising global prevalence of inflammatory bowel diseases (IBDs), such as Crohn's disease and ulcerative colitis, underscores the need to examine current and future IBD care costs. Direct health care expenses, including ambulatory visits, hospitalizations, and medications, are substantial, averaging $9,000 to $12,000 per person annually in high-income regions. However, …
The role of fungi in inflammatory bowel disease
Publication Year: 2025 Source: Indian J Gastroenterol PMID: 39153123
No Abstract
Claudin-2: A marker for a better evaluation of histological mucosal healing in inflammatory bowel diseases
Publication Year: 2025 Source: Dig Liver Dis PMID: 39155205 DOI: 10.1016/j.dld.2024.08.001
BACKGROUND: Histological mucosal healing has become a paramount target goal to achieve in the treatment of inflammatory bowel diseases. However, there is still a lack of agreement on the best way to reach this goal, since numerous histological scores are available worldwide. AIMS: We investigated whether claudin-2, a member of …
Seroprevalence of infectious bursal disease and its associated risk factors in Ethiopia: a systematic review and meta-analysis
Publication Year: 2025 Source: Avian Pathol PMID: 39155790 DOI: 10.1080/03079457.2024.2393613
The poultry population is an integral part of Ethiopia's Gross Domestic Product (GDP) but, due to various infectious diseases such as infectious bursal disease (IBD), the expected economic impact in the country remains limited. The status of the disease in Ethiopia is obscured; thus, a systematic review and meta-analysis were …
Comparative Risk of Serious Infection With Vedolizumab vs Anti-Tumor Necrosis Factors in Inflammatory Bowel Disease
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39158155
No Abstract
Otilonium bromide ameliorates pulmonary fibrosis in mice through activating phosphatase PPM1A
Publication Year: 2025 Source: Acta Pharmacol Sin PMID: 39160244
No Abstract
Severe Polypharmacy Increases Risk of Hospitalization Among Older Adults With Inflammatory Bowel Disease
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39162710 DOI: 10.14309/ajg.0000000000003036
INTRODUCTION: As the inflammatory bowel disease (IBD) patient population is aging, the prevalence of polypharmacy is rising. However, data exploring the prevalence, risk factors, and clinical outcomes associated with polypharmacy among older adults with IBD are limited. The aim of the study is to determine (i) prevalence of polypharmacy (>/=5 …
HLA-DQA1*05 Associates With Anti-Tumor Necrosis Factor Immunogenicity and Low Adalimumab Trough Concentrations in Inflammatory Bowel Disease Patients From the SERENE Ulcerative Colitis and Crohn's Disease Studies
Publication Year: 2025 Source: J Crohns Colitis PMID: 39162746
BACKGROUND AND AIMS: Anti-tumor necrosis factor (anti-TNF) therapies are commonly prescribed treatments for Crohn's disease (CD) and ulcerative colitis (UC). Many patients treated with anti-TNF therapy eventually develop anti-drug antibodies (ADAs). Understanding the factors associated with immunogenicity in anti-TNF-treated patients can help guide treatment. The Humira SERENE studies were Phase …
Spine and Sacroiliac Joint Involvement in Newly Diagnosed Patients With Inflammatory Bowel Disease: Clinical and MRI Findings From a Population-Based Cohort
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39162769 DOI: 10.14309/ajg.0000000000003039
INTRODUCTION: In patients with inflammatory bowel disease (IBD), co-occurring spondyloarthritis (SpA) leads to poorer outcomes and impaired quality of life, highlighting the importance of early detection and effective treatment. This is the first study to assess the prevalence and distribution of axial symptoms and magnetic resonance imaging (MRI)-detected involvement of …
Variability in morphology and immunohistochemistry of Crohn's disease-associated small bowel neoplasms: implications of Claudin 18 and Cadherin 17 expression for tumor-targeted immunotherapies
Publication Year: 2025 Source: Virchows Arch PMID: 39164422
No Abstract
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