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Anti-inflammatory and immunomodulatory effects of Glycyrrhiza uralensis fisch. On ulcerative colitis in rats: Role of nucleotide-binding oligomerization domain 2/receptor-interacting protein 2/nuclear factor-kappa B signaling pathway
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39929400
ETHNOPHARMACOLOGICAL RELEVANCE: As a traditional Chinese herb, Glycyrrhiza uralensis Fisch. exhibits a range of pharmacological activities, including anti-inflammatory, immunomodulatory and antifibrotic, which suggests its therapeutic potential for inflammatory bowel disease, and related mechanisms need to be further clarified. AIM OF THE STUDY: To evaluate in vivo anti-inflammatory effects of Glycyrrhiza …
Bifidobacterium longum NSP001-derived extracellular vesicles ameliorate ulcerative colitis by modulating T cell responses in gut microbiota-(in)dependent manners
Publication Year: 2025 Source: NPJ Biofilms Microbiomes PMID: 39929833
Recent studies have shown that intestinal commensal bacteria-derived vesicles may have potential effects in alleviating ulcerative colitis (UC). Although Bifidobacterium longum is widely used to prevent colitis, the potential role of B. longum-derived extracellular vesicles has yet to be explored. Here, we extracted B. longum NSP001-derived extracellular vesicles (NEVs) and …
Author Correction: Understanding the therapeutic toolkit for inflammatory bowel disease
Publication Year: 2025 Source: Nat Rev Gastroenterol Hepatol PMID: 39930068 DOI: 10.1038/s41575-025-01047-x
No Abstract
[ULCERATIVE COLITIS AND PRIMARY SCLEROSING CHOLANGITIS]
Publication Year: 2025 Source: Harefuah PMID: 39931022
ULCERATIVE COLITIS AND PRIMARY SCLEROSING CHOLANGITIS.
The Analysis and Comparison of Anti-Inflammatory and Antioxidant Characteristics of Postbiotic and Paraprobiotic Derived From Novel Native Probiotic Cocktail in DSS-Induced Colitic Mice
Publication Year: 2025 Source: Food Sci Nutr PMID: 39931269
Oxidative stress, particularly when precipitated by the intake of a diet rich in fats, has the potential to induce an inflammatory state. Therefore, it is crucial to consider the administration of agents possessing antioxidant and anti-inflammatory properties for the benefit of these patients. The objective of this study was to …
"Clinical epidemiology of inflammatory bowel disease among adults in the South Asian region: A systematic review and meta-analysis"
Publication Year: 2025 Source: Heliyon PMID: 39931471 DOI: 10.1016/j.heliyon.2025.e41840
OBJECTIVES: Inflammatory bowel disease (IBD) is an emerging disease in the South Asia. We conducted a systematic review to determine the characteristics and overall prevalence of IBD among South Asian adults. DESIGN: We searched the PubMed database and included descriptive, epidemiological studies with satisfactory methodological quality, reporting the epidemiology of …
Orally Administrated Precision Nanomedicine for Restoring the Intestinal Barrier and Alleviating Inflammation in Treatment of Inflammatory Bowel Disease
Publication Year: 2025 Source: ACS Appl Mater Interfaces PMID: 39931937 DOI: 10.1021/acsami.4c19742
Inflammatory bowel disease (IBD) presents a significant challenge in healthcare, characterized by its chronicity and complex pathogenesis involving genetic, immune, and environmental factors. Current treatment modalities, including anti-inflammatory drugs, immunomodulators, and biologics, often lack sufficient efficacy and are accompanied by adverse effects, necessitating the urgent search for therapeutic approaches targeting …
A Practical Guide for US and MR for Inflammatory Bowel Disease
Publication Year: 2025 Source: Radiology PMID: 39932412
No Abstract
How I Do It: Cross-sectional Imaging in Small-Bowel Crohn Disease and Ulcerative Colitis
Publication Year: 2025 Source: Radiology PMID: 39932413
Cross-sectional imaging, especially MR enterography (MRE) and intestinal US, plays an increasingly important role in the diagnosis and monitoring of Crohn disease. In this article, the authors share their approach to imaging Crohn disease, drawing on their clinical and research experience. They consider how to select the most appropriate modality …
Guidance for Fecal Microbiota Transplantation Trials in Ulcerative Colitis: The Second ROME Consensus Conference
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39932857 DOI: 10.1093/ibd/izaf013
BACKGROUND: Fecal microbiota transplantation (FMT) is emerging as a potential treatment modality for individuals living with inflammatory bowel disease (IBD). Despite its promise, the effectiveness of FMT for treating IBD, particularly for ulcerative colitis (UC), still requires thorough clinical investigation. Notwithstanding differences in methodologies, current studies demonstrate its potential for …
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