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Impact of glucocorticoids on patients' quality of life: a qualitative study assessing face validity and feasibility of the Steroid PRO in patients with inflammatory gastroenterology, respiratory and dermatology conditions
Publication Year: 2025 Source: BMJ Open PMID: 39909511
OBJECTIVES: The Steroid PRO is a treatment-specific patient-reported outcome questionnaire which measures the impact of glucocorticoids on health-related quality of life. It has 15 items grouped into 4 domains (Social impact, Impact on Appearance, Psychological Impact and Treatment Concerns). Initially developed and validated in rheumatic diseases, the Steroid PRO demonstrates …
Response to the Letter to the editor: "cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease" (CRCD-D-24-01694)
Publication Year: 2025 Source: Clin Res Cardiol PMID: 39909888
No Abstract
Knowledge of mothers on diaper dermatitis management and associated factors in Ethiopia
Publication Year: 2025 Source: Sci Rep PMID: 39910213
Diaper dermatitis is an inflammatory reactions of the skin under a diaper due to prolonged skin contact with irritants (urine and faeces), seborrhoea, allergic reaction, fungal (candida), and bacterial infections. It is more common in children aged 1-24 months, with the majority of instances occurring in newborns younger than one …
Fungal impacts on Earth's ecosystems
Publication Year: 2025 Source: Nature PMID: 39910383
Over the past billion years, the fungal kingdom has diversified to more than two million species, with over 95% still undescribed. Beyond the well-known macroscopic mushrooms and microscopic yeast, fungi are heterotrophs that feed on almost any organic carbon, recycling nutrients through the decay of dead plants and animals and …
Burden of inflammatory bowel disease in India: analysis of the Global Burden of Disease study from 1990 to 2019
Publication Year: 2025 Source: Intest Res PMID: 39910905 DOI: 10.5217/ir.2024.00134
BACKGROUND/AIMS: Inflammatory bowel disease (IBD) is increasing across the globe, more so in populous countries like India. We aimed to study the disease burden and epidemiological trends of IBD in India and look closer into the disease pattern across the country from 1990 to 2019. METHODS: The burden of IBD …
Secondary loss-of-response associated with intolerance to Janus kinase inhibitor in a boy with ulcerative colitis
Publication Year: 2025 Source: Pediatr Int PMID: 39911100
No Abstract
Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis
Publication Year: 2025 Source: Front Microbiol PMID: 39911249
INTRODUCTION: Periodontitis and inflammatory bowel disease are chronic inflammatory diseases with shared epidemiological, biological, and therapeutic associations. Given the similarities in their pathogenic factors, this study hypothesized that mesalazine, a key treatment agent for inflammatory bowel disease, could also be effective in managing periodontitis. METHODS: The antimicrobial effect of mesalazine …
Case report: A co-existing case of ulcerative colitis and dysferlinopathy in a male patient
Publication Year: 2025 Source: Front Med (Lausanne) PMID: 39911674 DOI: 10.3389/fmed.2024.1481780
Patients with inflammatory bowel disease (IBD) are at risk of developing malnutrition, severe dystrophic muscle weakness, and muscle atrophy. We present a case of a 33-year-old male patient who exhibited concurrent muscle atrophy, muscle weakness, diarrhea, and mucopurulent bloody stools. Notably, the patient reported that his household or family members …
Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function
Publication Year: 2025 Source: Front Microbiol PMID: 39911710 DOI: 10.3389/fmicb.2024.1496280
Numerous studies have confirmed that gut microbiota is a key driver in the occurrence and progression of inflammatory bowel disease (IBD). Based on the bacterial collection constructed in our previous studies, we founded that Bifidobacterium adolescentis AF91-08b2A has the potential beneficial function. We designed cohort studies, genomic studies and animal …
Association of First-Trimester Combined Inflammatory Markers (NLR, SII, SIRI, and AISI) With Poor Obstetric Outcomes in Pregnancies With Ulcerative Colitis
Publication Year: 2025 Source: Am J Reprod Immunol PMID: 39912620
AIM: To compare the first-trimester combined inflammatory markers between pregnant women diagnosed with ulcerative colitis (UC) and healthy pregnant women. Furthermore, to investigate the predictive value of these markers for adverse obstetric outcomes in pregnant women affected by UC. METHODS: In this retrospective study, data were collected from pregnant women …
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