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Short-chain fatty acid: An updated review on signaling, metabolism, and therapeutic effects

Publication Year: 2024 Source: Crit Rev Food Sci Nutr PMID: 36154353

Fatty acids are good energy sources (9 kcal per gram) that aerobic tissues can use except for the brain (glucose is an alternative source). Apart from the energy source, fatty acids are necessary for cell signaling, learning-related memory, modulating gene expression, and functioning as cytokine precursors. Short-chain fatty acids (SCFAs) …

Latilactobacillus sakei: a candidate probiotic with a key role in food fermentations and health promotion

Publication Year: 2024 Source: Crit Rev Food Sci Nutr PMID: 35997270

Latilactobacillus sakei is used extensively in industrial production and food fermentations. The species is primarily derived from fermented meat and vegetable products and is also found in human feces. Genomics and metabolomics have revealed unique metabolic pathways in L. sakei and molecular mechanisms underlying its competitive advantages in different habitats, …

The use of vitamin D for patients with inflammatory bowel diseases

Publication Year: 2024 Source: Int J Vitam Nutr Res PMID: 36017738 DOI: 10.1024/0300-9831/a000764

As vitamin D (VD) plays an essential role in inflammatory bowel diseases (IBD), this systematic review aimed to update the participation of this vitamin in the prevention or remission of these diseases. This review has included studies in MEDLINE-PubMed, EMBASE, and Cochrane databases. The authors have followed PRISMA (Preferred Reporting …

Outcomes of "Anterior Versus Posterior Divisional Branches of the Hypogastric Artery as Distal Landing Zone for Iliac Branch Devices": The International Multicentric R3OYAL Registry

Publication Year: 2024 Source: J Endovasc Ther PMID: 36113081 DOI: 10.1177/15266028221120513

OBJECTIVE: The aim of this multicentric registry was to assess the outcomes of "anteRior versus posteRior divisional bRanches Of the hYpogastric artery as distAl landing zone for iLiac branch devices (R3OYAL)." METHODS: The main exposure of interest for the purpose of this study was the internal iliac artery (IIA) divisional …

Live Typhoid and Yellow Fever Vaccines Administered to a Patient With Ulcerative Colitis on Vedolizumab

Publication Year: 2024 Source: ACG Case Rep J PMID: 39866528

No Abstract

Gastric Acid Suppression Is Associated With Higher Rates of Colectomy in Patients With Inflammatory Bowel Disease

Publication Year: 2024 Source: Gastro Hep Adv PMID: 39866722

No Abstract

Caspase-4 Has Potential Utility as a Colorectal Tissue Biomarker for Dysplasia and Early-Stage Cancer

Publication Year: 2024 Source: Gastro Hep Adv PMID: 39866724 DOI: 10.1016/j.gastha.2024.09.007

BACKGROUND AND AIMS: Colorectal cancer (CRC) is the second most deadly cancer globally. The rapidly rising incidence rate of CRC, coupled with increased diagnoses in individuals <50 years, indicates that early detection of CRC, and those at an increased risk of CRC development, is paramount to improve the survival rates …

Infliximab Precision Dosing in Inflammatory Bowel Disease (IBD) Patients: A Review of Current Literature

Publication Year: 2024 Source: Cureus PMID: 39867090 DOI: 10.7759/cureus.76424

The therapeutic failure of infliximab therapy remains a challenge in patients with inflammatory bowel disease (IBD), and dose optimization is often required. Accelerated or intensified regimes showed value in treating patients in the acute setting with high CRP or low albumin levels, which are suggested by recent guidelines; however, evidence …

Assessing hard and loose "endpoints": comparison of patient and expert Bristol Stool Scale scoring of 2280 fecal samples

Publication Year: 2024 Source: F1000Res PMID: 39872194

No Abstract

Exploring Dual-Targeted Therapy in the Management of Moderate to Severe Inflammatory Bowel Disease: A Retrospective Study

Publication Year: 2024 Source: Crohns Colitis 360 PMID: 39877297 DOI: 10.1093/crocol/otae057

BACKGROUND: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), often results in significant morbidity among patients with moderate to severe forms. While biologics and small molecules are effective in inducing remission, many patients experience refractory disease or extraintestinal manifestations. This study assesses the safety and efficacy …

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