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How to Approach the Difficult Perineum in Crohn's Disease
Publication Year: 2024 Source: Clin Colon Rectal Surg PMID: 39944307
No Abstract
Artificial intelligence-enabled advanced endoscopic imaging to assess deep healing in inflammatory bowel disease
Publication Year: 2024 Source: eGastroenterology PMID: 39944363 DOI: 10.1136/egastro-2024-100090
Endoscopic remission is the primary long-term therapeutic goal in inflammatory bowel disease (IBD). The assessment of this therapeutic target typically relies on white light endoscopy (WLE) combined with histological sampling. Nonetheless, distinguishing between endoscopic mild, patchy inflammation and quiescent disease can be challenging, and discrepancies have been observed between endoscopic …
To explore the causal association between the serum lipid profile and inflammatory bowel disease using bidirectional Mendelian randomisation analysis
Publication Year: 2024 Source: eGastroenterology PMID: 39944468 DOI: 10.1136/egastro-2023-100034
BACKGROUND: Despite studies confirming that patients with inflammatory bowel disease (IBD) present with dyslipidaemia, the associations between IBD and the serum lipid profile have not been determined. The present study aimed to investigate the causal relationship between the serum lipid profile and IBD risk and elucidate the nature of the …
Prebiotic selection influencing inflammatory bowel disease treatment outcomes: a review of the preclinical and clinical evidence
Publication Year: 2024 Source: eGastroenterology PMID: 39944472 DOI: 10.1136/egastro-2023-100055
Inflammatory bowel disease (IBD) is characterised by chronic inflammation in the gastrointestinal tract, with unclear aetiology but with known factors contributing to the disease, including genetics, immune responses, environmental factors and dysbiosis of the gut microbiota. Existing pharmacotherapies mainly target the inflammatory symptoms of disease, but recent research has highlighted …
Reproductive and sexual health concerns in gastrointestinal illness: a narrative review
Publication Year: 2024 Source: Transl Gastroenterol Hepatol PMID: 39944576 DOI: 10.21037/tgh-24-38
BACKGROUND AND OBJECTIVE: Gastrointestinal (GI) disorders, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), can have a profound and widespread impact on quality of life, including on reproductive and sexual functioning. However, reproductive and sexual concerns are rarely addressed in GI appointments and patients desire more information and …
Pathogenesis and precision medicine for predicting response in inflammatory bowel disease: advances and future directions
Publication Year: 2024 Source: eGastroenterology PMID: 39944752 DOI: 10.1136/egastro-2023-100006
The pathogenesis of inflammatory bowel disease (IBD) is complex and multifactorial. Undertreated disease has substantial individual and societal consequences. Current patient classification and subsequent positioning of IBD therapy are based on crude, readily accessible clinical data. These broad parameters are unlikely to reflect underlying molecular profiles and may account for …
A Comparison of Intravenous Infliximab Versus Subcutaneous Infliximab on Remission Rates, Safety, Costs, Patient Preferences in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Publication Year: 2024 Source: Gastro Hep Adv PMID: 39944928 DOI: 10.1016/j.gastha.2024.11.004
BACKGROUND AND AIMS: Infliximab, widely used as a mainstay treatment of inflammatory bowel disease (IBD), is traditionally administered intravenously. The subcutaneous (SC) formulation appears to offer a more convenient route of administration. This is a systematic review and meta-analysis comparing the outcomes of intravenous (IV) and SC routes of administration …
[A Case of Lynch Syndrome Diagnosed with MSI-H Ulcerative Colitis-Associated Colon Cancer]
Publication Year: 2024 Source: Gan To Kagaku Ryoho PMID: 39948952
No Abstract
Fetal and Early-Life Antibiotics and Risk of Pediatric Inflammatory Bowel Disease: A Population-Based Nationwide Register Study
Publication Year: 2024 Source: J Pediatr Clin Pract PMID: 39949419 DOI: 10.1016/j.jpedcp.2024.200096
OBJECTIVE: To assess whether antibiotic exposure prenatally and before 2 years of age is associated with subsequent pediatric inflammatory bowel disease (PIBD), as earlier studies diverge substantially in risk estimations or do not include prenatal exposure. METHODS: We performed a register-based cohort study including all children in Norway born 2004-2012 …
Persistence of newly prescribed 5-aminosalicylic acid in patients with ulcerative colitis: A nationwide comprehensive database study
Publication Year: 2024 Source: PLoS One PMID: 39775682
No Abstract
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